Adryana Cordeiro¹*, Silvia Elaine Pereira^1,2, Bruno Campos¹, Carlos José Saboya², Andrea Ramalho^1,3

¹Micronutrients Research Center (NPqM), Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil
²Multidisciplinary Center of Bariatric and Metabolic Surgery Carlos Saboya, Rio de Janeiro, Brazil.
³Department of Social Applied Nutrition; Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

*Corresponding Author: Adryana Cordeiro, Micronutrients Research Center (NPqM), Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

Received: May 23, 2024; Published: June 30, 2024

Abstract

Introduction: There is a subgroup of individuals with obesity, called with metabolically healthy obesity (MHO) phenotype, who remains insulin-sensitive, and they may be more protected from metabolic disorders. Low vitamin D serum concentrations were observed in individuals with obesity, mainly with high abdominal adiposity.

Methods: Descriptive cross-sectional study was conducted with individuals, aged ≥ 20 < 60 years. Body variables were evaluated, and metabolic parameters [blood pressure and blood glucose, insulin, lipid profile, high-sensitivity c- reactive protein (hs-CRP) and (25(OH)D)] were obtained. The cut-off point for vitamin D deficiency (VDD) was ≤20 ng/mL. Individuals were classified as MUHO according to four different definitions.

Results: This study comprised 232 individuals with obesity (BMI ≥ 35 Kg/m²); 178 female (76.7%). MUHO phenotype was observed in 67.7%, 76.7%, 71,5% and 82,7% according to NCEP/ATPIII, HOMA-IR, Wildman, and Karelis definitions, respectively. Only for the HOMA-IR definition, the mean value of 25(OH)D showed a significant difference between the phenotype groups (p=0.011). Among all criteria to classify obesity phenotype, only in HOMA-IR presented some predictors of MUHO in individuals with VDD.

Conclusion: The results show high prevalence of inadequacy of serum concentrations of 25(OH)D in individuals with MUHO phenotype, mainly classified by HOMA-IR definition.

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Citation

Citation: Adryana Cordeiro., et al. “Vitamin D Nutritional Status and its Relationship with Body Variables in Individuals with Obesity According to Classification of Obesity Phenotype for Different Criteria". Acta Scientific Nutritional Health 8.7 (2024): 106-115.

Copyright

Copyright: © 2024 Adryana Cordeiro., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.