Atharva Dodya¹, Srilatha Bashetti²*, Ganesh Bheemanaboina³, Umrana Mirza⁴, Raghavendra Rao MV⁵ and Joya Rani Devarashetty⁶

¹Student, Second MBBS, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India
²Associate Professor, Department of Biochemistry, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India
³Ph.D Scholar, Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India
⁴Assistant Professor, Department of Biochemistry, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India
⁵Central Research Laboratory, Apollo Institute of Medical Sciences and Research, Hyderabad, Telangana, India
⁶Principal and Professor, Department of Physiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India

*Corresponding Author: Srilatha Bashetti, Associate Professor, Department of Biochemistry, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India.

Received: January 11, 2024; Published: February 06, 2024

Abstract

From an evolutionary point of view, our nutrition and gut health are accustomed to our environment. There is a well-marked difference in dietary habits specific to a region. These dietary habits vary from region to region. Due to technological advancements and the cosmopolitan development of cities, everything is just a tap away. The evolution of technology has surpassed the evolution of our bodies. In nature, organisms evolve with the evolution of their surroundings at the same pace, and the balance is maintained. sugar or carbs are the most consumed food, have higher cravings, and are easily digested. The fact is never denied that whatever type of food we consume, carbs, fat, or protein should ultimately get converted to an instant energy molecule to utilize instantly. Yet another accepted fact is that excess glucose is stored as fat in the body. Glucose can form both cholesterol and triglycerides. Cholesterol is essential for the production of vitamin D, hormones, and bile acids. Triglycerides are a storage form of fat. The excess glucose is converted to fatty acids. These fatty acids are further converted to cholesterol or triglycerides, a common precursor being acetyl CoA. The amount of glucose that is converted to cholesterol or triglycerides depends on several factors, including the person's diet, exercise habits, and genetics. Many studies are taken up to understand the link between glucose and lipid metabolism even at molecular level but still this field of research is unsuccessful. It is a complex pathway hence, its mechanism remains obscure. The common conclusion derived from various research studies related glucose is that high glucose will contribute for fat synthesis and excess fats cause insulin resistance and β- cell dysfunction and has the same effect exclusively with high fat content too. One can derive the conclusion that hypertriglyceridemia is not just a complication but also a cause of abnormal glucose metabolism. Glucose is indispensable for the body functions and moderation (self-restraint) is the only remedy to avoid its potential toxic effects.

Keywords: Glucose; Cholesterol; Healthy Lifestyle; Metabolic Syndrome

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Citation

Citation: Srilatha Bashetti., et al. “Glucose- “The Culprit” and Cholesterol- “The Victim.” Balanced Diet with Healthy Lifestyle is the only Solution to Prevent Metabolic Syndrome".Acta Scientific Nutritional Health 8.3 (2024): 14-21.

Copyright

Copyright: © 2024 Srilatha Bashetti., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.