Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Case Report Volume 7 Issue 11

Fetal Rhabdomyoma: Case Report

Francisca Rodríguez Escobar1, Cristóbal Arroyo Zambrano2, Manuel Alvarez Vaccaro3 and Alejandro Alvarez Jara4*

1Physician-surgeon, Cesfam San Pedro de la Paz Concepción, Chile
2Medical student, Faculty of Medicine Universidad Católica de la Santísima, Concepción, Chile
3Medical student, Faculty of Medicine Universidad del Desarrollo Santiago, Chile
4Pediatrician and Pediatric Cardiologist, Fetal Exploration Unit Hospital Guillermo, Grant Benavente Concepción, Chile

*Corresponding Author: Alejandro Alvarez Jara, Pediatrician and Pediatric Cardiologist, Fetal Exploration Unit Hospital Guillermo, Grant Benavente Concepción, Chile.

Received: September 26, 2023; Published: October 24, 2023

Abstract

Rhabdomyoma corresponds to the most common fetal cardiac tumor, and can affect any point of the cardiac muscle, generating various manifestations. Very large tumors can cause hemodynamic obstruction, requiring surgery.

Its development is related to tuberous sclerosis, which produces abnormal cell proliferation, which is why sirolimus, a rapamycin (mTOR) inhibitor, has been used for its antitumor activity. A clinical case is presented where the cardiac rhabdomyoma, despite generating great obstruction in the outlet of the left ventricle, was completely resolved after the administration of sirolimus, without generating adverse effects or the need for surgery.

Keywords: Rhabdomyoma; Cardiac Tumor; Prenatal Diagnosis

References

  1. Chía- Vázquez NG., et al. “Importancia del rabdomioma cardiaco en la población pediátrica. Experiencia de 39 años. Serie de casos”. Archivos de Cardiología de México (2021).
  2. Chen X-Q., et al. “Sirolimus Can Increase the Disappearance Rate of Cardiac Rhabdomyomas Associated with Tuberous Sclerosis: A Prospective Cohort and Self- Controlled Case Series Study”. The Journal of Pediatrics (2021).
  3. Martinez- Morales MC., et al. “Múltiples rabdomiomas intracardiacos en vida fetal simulando atresia tricuspídea al nacimiento”. Perinatología y Reproducción Humana 36.2 (2022).
  4. Dr. Marco Tulio Gómez Cerdas and Dr Johnny Alejandro Vargas Morales. “Esclerosis tuberosa”. Revista Médica Sinergia 4.3 (2019): 21-37.
  5. Park H., et al. “Sirolimus therapy for fetal cardiac rhabdomyoma in a pregnant woman with tuberous sclerosis”. Korean Society of Obstetrics and Gynecology (2019).
  6. Somoza Marino. “Cardiopatías congénitas cardiología perinatal segunda edición” (2015): 444.
  7. Alfred Abuhamad and Rabih Chaoui. “Ecocardiografía fetal tercera edición Ediciones Journal (2019): 537-546.
  1. Sasongko TH., et al. “Rapamycin and rapalogs for tuberous sclerosis complex”. Cochrane Database of Systematic Reviews 7 (2016): CD011272.
  2. Bader RS., et al. “Fetal rhabdomyoma: prenatal diagnosis, clinical, outcome, and incidence of associated tuberous sclerosis complex”. The Journal of Pediatrics 143 (2003): 620-624.

Citation

Citation: Alejandro Alvarez Jara.,et al. “Fetal Rhabdomyoma: Case Report".Acta Scientific Nutritional Health 7.11 (2023): 21-23.

Copyright

Copyright: © 2023 Alejandro Alvarez Jara.,et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.316

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