Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Aticle Volume 7 Issue 7

Nutrition and Breast Cancer in the Provincial Hospital Jason Sendwe, in Lubumbashi: A Case Control Study, January 2019 to December 2020

Junichiro Yamamoto1*, Wataru Shioyama2, Hideo Ikarugi3, Yoshinobu Ijiri4 Muneshige Shimizu5, Tomoya Takashima6, Hiroyuki Kikukawa7, Masahiro Murakami6, Kazunori Otsui8, Jaap Jan Zwaginga9 and Kjell S Sakariassen10

1Kobe Gakuin University, Kobe, Japan
2Department of Internal Medicine, Division of Cardiovascular Medicine, Shiga University of Medical Science, Japan
3School of Economics and Management, University of Hyogo, Kobe, Japan
4Department Of Health and Nutrition, Osaka Shoin Women’s University, Osaka, Japan
5Department of Fishers, School of Marine Science, Japan
6Faculty of Pharmacy, Osaka Ohtani University, Osaka 584-8540, Japan
7The Faculty of Contemporary Social Studies, Kobe Gakuin University, Kobe 650-8586, Japan
8Department of General Internal Medicine, Kobe University Hospital, Kobe 650-0017, Japan
9Department of Hematology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands; CCTR, Sanquin Blood Supply, 1066 CX Amsterdam, The Netherlands
10I-13900 Biella, BI, Italy

*Corresponding Author: Junichiro Yamamoto, Kobe Gakuin University, Kobe, Japan.

Received: May 10, 2023; Published: June 29, 2023


Ex vivo shear-induced and in vivo helium-neon laser-induced thrombosis/fibrinolysis tests were compared in animal models. The results of this paired ex vivo global thrombosis test (GTT) and in vivo thrombosis test comparison showed that both tests were wellmatched. Thrombotic disorders are classified as type I, II, or III. Type I is due to increased thrombotic and decreased fibrinolytic activity, while type II is caused only by decreased fibrinolytic activity. Type III is caused by endothelial dysfunction which is independent of thrombotic and fibrinolytic activities of blood. Based on these animal experiments, specific medications can be considered also for humans. Daily intake of an antithrombotic diet and suitable individual-matched exercise may prevent thrombotic episodes and aid rehabilitation.

Keywords: Endogenous Fibrinolysis; Platelet Aggregation; Shear-Induced Thrombosis; Cancer-Associated Thrombosis; Antithrombotic Drug; Physical Exercise; Antithrombotic Diet


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Citation: Junichiro Yamamoto., et al. “Investigations into the Pathomechanism of thrombotic Disorders with an Ex Vivo Global Test Performed from Non-Anticoagulated Blood: From Animal Experiments to Bedside Application".Acta Scientific Nutritional Health 7.7 (2023): 119-129.


Copyright: © 2023 Junichiro Yamamoto., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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