Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 7 Issue 7

Anthropometric Indices and Clinical Manifestations After Gluten Free Diet Therapy and Nutritional Education in Pediatric Patients with Celiac Disease

Zahra Setavand1, Maryam Ekramzadeh2*, Naser Honar3 and Sara Ekramzadeh4

1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
2Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
3Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Psychiatry, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

*Corresponding Author: Maryam Ekramzadeh, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Received: May 24, 2023; Published: June 22, 2023

Abstract

Celiac disease (CD) is an immune enteropathy with wide heterogeneous symptoms which can affect children’s growth. Since gluten-free diet (GFD) is the only treatment available for CD, the aim of the present study was to evaluate anthropometric indices and symptoms recovery in children with CD after treatment with a GFD. Seventy-four children with age of 2-18 years old and diagnosed with CD recruited from XXX specialized clinic in a quasi-experimental retrospective study. Height, weight, Body Mass Index (BMI), malnutrition based on WHO growth charts, and clinical symptoms were collected from patients’ records. A GFD was prescribed by a nutritionist and patient's nutritional needs including the amount of calories and the percentage of macronutrients were calculated. The results indicated a significant difference in height (p < 0.001), weight (p < 0.001), and height z-score (p = 0.003) before and after the intervention. No difference was seen in number of patients in different height z-scores. However, number of patients with low body weight and BMI for age had decreased at the end of study compared to the beginning. There was a remarkable reduction in clinical symptoms including diarrhea, flatulence, abdominal pain, constipation, hair loss, skin dryness and weight loss (p < 0.05). However, the number of patients with abdominal distention increased significantly. To sum up, adherence to GFD may lead to improvements in body weight and height in underweight children. Moreover, GFD have beneficial effects in reduction of CD manifestations. Further prospective trials are warranted.

Keywords: Celiac Disease; Gluten; Height; Body Weight

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Citation

Citation: Zahra Setavand., et al. “Anthropometric Indices and Clinical Manifestations After Gluten Free Diet Therapy and Nutritional Education in Pediatric Patients with Celiac Disease".Acta Scientific Nutritional Health 7.7 (2023): 79-84.

Copyright

Copyright: © 2023 Maryam Ekramzadeh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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