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Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Review Article Volume 7 Issue 3

Nutritional Treatments in Arthritis Types

Aleyna ŞAHİN* and Ayşe GÜNEŞ BAYIR

Department of Nutrition and Dietetics, Faculty of Health Sciences, Bezmialem Vakif University, İstanbul, Türkiye

*Corresponding Author: Aleyna ŞAHİN, Department of Nutrition and Dietetics, Faculty of Health Sciences, Bezmialem Vakif University, İstanbul, Türkiye.

Received: February 07, 2023; Published: February 24, 2023


Arthritis is a health problem that has different forms, primarily rheumatoid arthritis (RA), Osteoarthritis (OA) and GUT arthritis. It is stated as a degenerative joint disease that affects the cartilage and many of the tissues around it. Arthritis is an autoimmune disease characterized by painful joints, joint stiffness and limitation of movement, and intense inflammatory responses. Factors such as cigarette consumption, infectious agents, environmental pollution and chronic stress have been found to trigger intense inflammatory responses in arthritis. Apart from these factors, the role of nutrition has recently been suggested with increasing evidence. In some studies, fruit, vegetable or meat intake has been associated with diet and disease status, but no definitive conclusion has been reached. It has been observed that the prevalence of arthritis is lower in those who eat the Mediterranean diet while other diet types also have a relieving effect on the symptoms of the disease. Vegetarian diet, gluten-free diet, Mediterranean diet, elimination diet or intermittent fasting diet are some of these diets. Genetics is also thought to have an effect on arthritis. Genetic and environmental factors are thought to play an important role in the pathophysiology and occurrence of the disease. The data identify diet as an environmental factor in the development of arthritis, with diet increasing the inflammatory response in genetically predisposed individuals. Recently, it has been suggested that obesity, diabetes and metabolic syndrome are important risk factors for the development of arthritis. The treatment of arthritis is limited. In general, there is a treatment that reduces the symptoms related to the patient's symptoms or if there is a serious dysfunction in the joint, there are treatment options with total joint replacement. Of the basic pathophysiological mechanisms in the formation of arthritis, increased inflammation and impaired immune system regulation play an important role in the development of comorbidities. It is known that many comorbidities accompany arthritis. Some of these comorbidities are cardiovascular diseases, malignancies, infections, and osteoporosis. In addition, comorbidities can significantly increase the risk of mortality. The aim of this review was to reveal nutritional treatments based on arthritis types according to current approaches.

Keywords: Arthritis; Mediterranean Diet; Elimination Diet; Obesity; Inflammatory Response


  1. Martínez M Revenga., et al. "Artritis reumatoide”. Medicine-Programa de Formación Médica Continuada Acreditado30 (2021): 1669-1680.
  2. Kuusalo L., et al. "Metabolic osteoarthritis - relation of diabetes and cardiovascular disease with knee osteoarthritis”. Osteoarthritis and Cartilage2 (2021): 230-234.
  3. Basu Arpita., et al. "Dietary fruits and arthritis”. Food and Function1 (2018): 70-77.
  4. Philippou Elena., et al. "Rheumatoid arthritis and dietary interventions: systematic review of clinical trials”. Nutrition Reviews4 (2021): 410-428.
  5. Litwic Anna., et al. "Epidemiology and burden of osteoarthritis”. British Medical Bulletin 105 (2013): 185-199.
  6. Mariani Cesare., et al. "Use of bone marrow derived mesenchymal stem cells for the treatment of osteoarthritis: A retrospective long-term follow-up study”. Journal of Clinical Orthopaedics and Trauma 36 (2022): 102084.
  7. Primorac Dragan., et al. "Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations”. Genes8 (2020): 854.
  8. Yuan Hui., et al. "Lubricants for osteoarthritis treatment: From natural to bioinspired and alternative strategies”. Advances in Colloid and Interface Science 311 (2023): 102814.
  9. Lim Yuan Z., et al. "Recommendations for weight management in osteoarthritis: A systematic review of clinical practice guidelines”. Osteoarthritis and Cartilage Open4 (2022): 100298.
  10. Bennell Kim L., et al. "Platelet-Rich Plasma for the Management of Hip and Knee Osteoarthritis”. Current Rheumatology Reports5 (2017): 24. 
  11. Messier Stephen P. “Diet and exercise for obese adults with knee osteoarthritis”. Clinics in Geriatric Medicine3 (2010): 461-477.
  12. Lee Ryan and Walter F Kean. “Obesity and knee osteoarthritis”. Inflammopharmacology2 (2012): 53-58.
  13. Bliddal H., et al. "Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review”. Obesity Reviews: An Official Journal of the International Association for the Study of Obesity7 (2014): 578-586.
  14. Lopez Hector L. “Nutritional interventions to prevent and treat osteoarthritis. Part I: focus on fatty acids and macronutrients”. PM and R: The Journal of Injury, Function, and Rehabilitation5 (2012): S145-154.
  15. Pitaraki Evaggelia E. “The role of Mediterranean diet and its components on the progress of osteoarthritis”. Journal of Frailty, Sarcopenia and Falls3 (2017): 45-52.
  16. Radu Andrei-Flavius and Simona Gabriela Bungau. “Management of Rheumatoid Arthritis: An Overview”. Cells11 (2021): 2857.
  17. Gioia Chiara., et al. "Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations?”. Nutrients5 (2020): 1456.
  18. Häger Julian., et al. "The Role of Dietary Fiber in Rheumatoid Arthritis Patients: A Feasibility Study”. Nutrients10 (2019): 2392.
  19. Bullock Jacqueline., et al. "Rheumatoid Arthritis: A Brief Overview of the Treatment”. Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre6 (2018): 501-507.
  20. Baker Rahaf., et al. "Risk factors for osteoporosis and fractures in rheumatoid arthritis”. Best Practice and Research. Clinical Rheumatology3 (2022): 101773.
  21. McCann Kelly. “Nutrition and rheumatoid arthritis”. Explore (New York, N.Y.)6 (2007): 616-618. 
  22. Gioia Chiara., et al. "Dietary Habits and Nutrition in Rheumatoid Arthritis: Can Diet Influence Disease Development and Clinical Manifestations?” Nutrients5 (2020): 1456.
  23. Rondanelli, Mariangela., et al. "Ideal food pyramid for patients with rheumatoid arthritis: A narrative review”. Clinical Nutrition (Edinburgh, Scotland)3 (2021): 661-689.
  24. Miggiano GAD and L Gagliardi. “Dieta, nutrizione e artrite reumatoide” [Diet, nutrition and rheumatoid arthritis]”. La Clinica Terapeutica3 (2005): 115-123.
  25. Richardson DC., et al. "Nutritional management of osteoarthritis”. The Veterinary Clinics of North America. Small Animal Practice4 (1997): 883-911.
  26. Dourado Eduardo., et al. "Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis”. Nutrients11 (2020): 3504.
  27. Jiang Yan., et al. "Therapeutic Implications of Diet in Inflammatory Bowel Disease and Related Immune-Mediated Inflammatory Diseases”. Nutrients3 (2021): 890.
  28. Smedslund Geir., et al. "Effectiveness and safety of dietary interventions for rheumatoid arthritis: a systematic review of randomized controlled trials”. Journal of the American Dietetic Association5 (2010): 727-735.
  29. Gaby AR. “Alternative treatments for rheumatoid arthritis”. Alternative Medicine Review: A Journal of Clinical Therapeutic6 (1999): 392-402.
  30. Clebak Karl T., et al. "Gout: Rapid Evidence Review”. American Family Physician9 (2020): 533-538.
  31. Schlesinger Naomi. “Treatment of chronic gouty arthritis: it is not just about urate-lowering therapy”. Seminars in Arthritis and Rheumatism2 (2012): 155-165.
  32. Fang Zhen-hua and Hazibullah Waizy. “Current concepts in the treatment of gouty arthritis”. Orthopaedic Surgery1 (2013): 6-12.
  33. Zamudio-Cuevas Yessica., et al. "Monosodium urate crystals induce oxidative stress in human synoviocytes”. Arthritis Research and Therapy1 (2016): 117.
  34. Terkeltaub Robert. “What makes gouty inflammation so variable?” BMC Medicine1 (2017): 158.
  35. Eggebeen Aaron T. “Gout: an update”. American Family Physician6 (2007): 801-808.
  36. Hueskes Berdine AA., et al. "Use of diuretics and the risk of gouty arthritis: a systematic review”. Seminars in Arthritis and Rheumatism6 (2012): 879-889.
  37. Zhang Yingling., et al. "Gout and Diet: A Comprehensive Review of Mechanisms and Management”. Nutrients17 (2022): 3525.
  38. Saag Kenneth G and Hyon Choi. “Epidemiology, risk factors, and lifestyle modifications for gout”. Arthritis Research and Therapy1 (2006): S2.
  39. Yokose Chio., et al. "Dietary and Lifestyle-Centered Approach in Gout Care and Prevention”. Current Rheumatology Reports7 (2021): 51.
  40. Towiwat Patapong, and Zhan-Guo Li. “The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout”. International Journal of Rheumatic Diseases5 (2015): 495-501.
  41. Danve Abhijeet., et al. "Role of diet in hyperuricemia and gout”. Best Practice and Research. Clinical Rheumatology4 (2021): 101723.
  42. Choi Hyon K., et al. "Purine-rich foods, dairy and protein intake, and the risk of gout in men”. The New England Journal of Medicine11 (2004): 1093-103.
  43. Yokose Chio., et al. "The role of diet in hyperuricemia and gout”. Current Opinion in Rheumatology2 (2021): 135-144.
  44. Singh Jasvinder A and Angelo Gaffo. “Gout epidemiology and comorbidities”. Seminars in Arthritis and Rheumatism3S (2020): S11-S16.


Citation: Aleyna ŞAHİN and Ayşe GÜNEŞ BAYIR. “Nutritional Treatments in Arthritis Types".Acta Scientific Nutritional Health 7.3 (2023): 85-91.


Copyright: © 2023 Aleyna ŞAHİN and Ayşe GÜNEŞ BAYIR. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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