Saber JEDIDI^1,2*, Foued ALOUI¹, Houcine SELMI¹, Kais RTIBI¹, Houssem SAMMARI² and Hichem SEBAI²

¹Laboratoire des Ressources Sylvo-Pastorales, Université de Jendouba, Institut Sylvo-Pastoral de Tabarka, Tunisie
²Unité de Physiologie Fonctionnelle et Valorisation des Bio-Ressources, Université de Jendouba, Institut Supérieur de Biotechnologie de Béja, Tunisie

*Corresponding Author: Saber JEDIDI, Laboratoire des Ressources Sylvo- Pastorales, Université de Jendouba, Institut Sylvo-Pastoral de Tabarka, Tunisie.

Received: December 06, 2022; Published: December 27, 2022

Abstract

Objectives: The present study aims to determine the inhibitory effects of Rosmarinus officinalis essential oils (ROEO) on gastrointestinal transit in rats as well as the involvement of its antimicrobial properties in such protection.

Methodology: The antibacterial power of the oils was evaluated against bacteria (2 Gram - bacteria, 2 Gram + bacteria) by the diffusion method on agar medium. The gastrointestinal transit (GIT) was assessed using charcoal meal method. In this respect, female Wistar rats were used and divided into six groups of eight each: control, ROEO treated groups. The last two groups were pretreated with clonidine and yohimbine, two reference molecules, which accelerate and delay TGI, respectively.

Results: Our results demonstrated that the SOEO exhibited a broad spectrum of antibacterial activity, with a great effect against Gram+ strains compared to the Gram-. On the other hand, in vivo study showed that the ROEO significantly, and dose dependently, decreased the GIT activity. However, clonidine and yohimbine respectively decreased (39.76%) and increased (13.93%) the GIT.

Conclusion: In conclusion, we suggest that ROEO had a potent inhibitory effect on gastrointestinal transit due in part to its antimicrobial properties.

Keywords: Antimicrobial Activity; Transit Gastrointestinal; Rosmarinus Officinalis; Essential Oils; Rat

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Citation

Citation: Saber JEDIDI., et al. “Antibacterial Capacity and Inhibitory Effect of Rosemary (Rosmarinus officinalis L.) Essential Oils on Gastrointestinal Transit in Rats".Acta Scientific Nutritional Health 7.1 (2023): 115-120.

Copyright

Copyright: © 2023 Saber JEDIDI., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.