Yulin Arditawati¹*, Darmono¹, Febe Christianto¹ and Widyastuti²

¹Department of Clinical Nutrition, Diponegoro University, Indonesia
²Department of Dermatovenereology, Diponegoro University, Indonesia

*Corresponding Author: Yulin Arditawati, Department of Clinical Nutrition, Diponegoro University, Indonesia.

Received: December 14, 2022; Published: December 26, 2022

Abstract

Malnutrition and skin problems are interrelated. Malnutrition may reduce the function of innate and adaptive immunity. There are immune cells in the skin that are crucial for host defense. A 62-year- old female patient was diagnosed with Toxic Epidermal Necrolysis (TEN) due to an unknown drug allergy and moderate to severe malnutrition. The patient had a history of inadequate intake for one year and has worsened during the last two weeks due to blistered and peeling skin, especially in the labium oris area after taking an unknown analgesic medication. Nutrition therapy with a target of 1900 kcal/day was administered and gradually increased to 2200 kcal/day through the enteral and parenteral route with a protein intake of 1.5 grams/kgIBW/day. Due to a history of food aversion to animal protein such as chicken, eggs, fish, cow's milk, and dairy products, soy-based polymeric formula and supplemental parenteral nutrition were administered to achieve nutrition requirements. Micronutrient supplementations including zinc, vitamin A, vitamin B complex, and vitamin C were given on day one of treatment. The patient experienced side effects due to systemic corticosteroids in the form of the moon face, severe muscle wasting, hyperglycemia, and hypertension. At the end of the treatment period, there were metabolic improvements such as wound healing without secondary skin infection and improvement of albumin serum from 2,3g/dL to 3,3g/dL.

Keywords: Aversion, Corticosteroid; Malnutrition; Toxic Epidermal Necrolysis

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Citation

Citation: Yulin Arditawati., et al. “62-Year-Old Woman with Severe Malnutrition and Toxic Epidermal Necrolysis".Acta Scientific Nutritional Health 7.1 (2023): 96-102.

Copyright

Copyright: © 2023 Yulin Arditawati., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.