Drali Ouardia¹*, Arab Madina¹, Lamdjadani Noureddine², Guechi Zhor¹ and Berrah Hassina¹

¹Department of Pediatrics B, Epidemiology and Statistics Department, Hussein Dey, University Hospital Center, Algiers, Algeria
²Biochemistry Unit, Epidemiology and Statistics Department, Hussein Dey, University Hospital Center, Algiers, Algeria

*Corresponding Author: Drali Ouardia, Department of Pediatrics B, Epidemiology and Statistics Department. Hussein Dey, University Hospital Center, Algiers, Algeria.

Received: July 04, 2022; Published: August 18, 2022

Abstract

  Knowledge of vitamin D has made great progress in recent years with the identification of its receptors (VDR) in most tissues, passing it from the role of a purely phosphocalcic and bone tropic hormone to that of a hormone playing a role global health.

  In Algeria, we lack epidemiological studies to assess the vitamin D status of healthy and supplemented infants. Through this work, we propose to determine the vitamin D status, to assess the vitamin D nutritional intake of healthy infants and to identify risk factors related to hypovitaminosis D in order to target and treat populations at risk.

Results: The analysis covers 395 infants aged between 9 and 24 months recruited during the 4 seasons. The mean age was

  11.5 ± 1.3 months. The sex ratio was 1.5. The average daily dietary intake of vitamin D was estimated at 167 IU/d (4.1µg/d). 90% of the children had low daily food intakes (less than 200IU/d).

The mean total vitamin D level in our series was 15.6 ± 4.4 ng/ml, significantly lower than current recommendations (25 OHD > 20 ng/ml) with a mean PTH level of 38 ± 4.2 pg/ml.

  The prevalence of vitamin D deficiency increased from 50% in the 12-24 month age group, to 75% in the 09-12 month group in winter, and from 21% in children aged between 12 and 24 months to 64% in children aged between 09.

  The risk of vitamin D deficiency is associated with individual factors that cannot be modified (skin pigmentation), lifestyle habits (lack of sunlight, insufficient dietary intake of vitamin D and) and environmental factors (season).

Conclusion: The magnitude of the prevalence of hypovitaminosis D in infants with high bone growth velocity and increased vitamin D requirements prompts us to question vitamin D drug supplementation. Six-monthly systematic vitamin D supplementation would be necessary for children with risk factors as well as children without risk factors in the winter period according to the results of our study.

Keywords: 2 5 OHD; Vitamin D Intake; Infants; PTH; Algeria

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Citation

Citation: Drali Ouardia., et al. “Risk Factors for Low Serum 25 OHD Concentrations in Healthy Infants in Algeria". Acta Scientific Nutritional Health 6.9 (2022): 49-54.

Copyright

Copyright: © 2022 Drali Ouardia., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.