Drali Ouardia1*, Arab Madina1, Lamdjadani Noureddine2, Guechi Zhor1 and Berrah Hassina1
1Department of Pediatrics B, Epidemiology and Statistics Department, Hussein Dey, University Hospital Center, Algiers, Algeria
2Biochemistry Unit, Epidemiology and Statistics Department, Hussein Dey, University Hospital Center, Algiers, Algeria
*Corresponding Author: Drali Ouardia, Department of Pediatrics B, Epidemiology and Statistics Department. Hussein Dey, University Hospital Center, Algiers, Algeria.
Received: July 04, 2022; Published: August 18, 2022
Knowledge of vitamin D has made great progress in recent years with the identification of its receptors (VDR) in most tissues, passing it from the role of a purely phosphocalcic and bone tropic hormone to that of a hormone playing a role global health.
In Algeria, we lack epidemiological studies to assess the vitamin D status of healthy and supplemented infants. Through this work, we propose to determine the vitamin D status, to assess the vitamin D nutritional intake of healthy infants and to identify risk factors related to hypovitaminosis D in order to target and treat populations at risk.
Results: The analysis covers 395 infants aged between 9 and 24 months recruited during the 4 seasons. The mean age was
11.5 ± 1.3 months. The sex ratio was 1.5. The average daily dietary intake of vitamin D was estimated at 167 IU/d (4.1µg/d). 90% of the children had low daily food intakes (less than 200IU/d).
The mean total vitamin D level in our series was 15.6 ± 4.4 ng/ml, significantly lower than current recommendations (25 OHD > 20 ng/ml) with a mean PTH level of 38 ± 4.2 pg/ml.
The prevalence of vitamin D deficiency increased from 50% in the 12-24 month age group, to 75% in the 09-12 month group in winter, and from 21% in children aged between 12 and 24 months to 64% in children aged between 09.
The risk of vitamin D deficiency is associated with individual factors that cannot be modified (skin pigmentation), lifestyle habits (lack of sunlight, insufficient dietary intake of vitamin D and) and environmental factors (season).
Conclusion: The magnitude of the prevalence of hypovitaminosis D in infants with high bone growth velocity and increased vitamin D requirements prompts us to question vitamin D drug supplementation. Six-monthly systematic vitamin D supplementation would be necessary for children with risk factors as well as children without risk factors in the winter period according to the results of our study.
Keywords: 2 5 OHD; Vitamin D Intake; Infants; PTH; Algeria
Citation: Drali Ouardia., et al. “Risk Factors for Low Serum 25 OHD Concentrations in Healthy Infants in Algeria". Acta Scientific Nutritional Health 6.9 (2022): 49-54.
Copyright: © 2022 Drali Ouardia., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.