Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 6 Issue 7

Iron Deficiency Anemia in Children Younger than Six Months and Time of Umbilical Cord Clamping. Anemia in 6 Months Old Infants and Delayed Clamping of the Umbilical Cord

Fabíola Figueiredo Nejar1, Marina Ferreira Rea2* and Ana Maria Segall-Corrêa3

1FFN - Nutritionist, PhD in Collective Health from the Department of Preventive and Social Medicine, Faculty of Medical Sciences - University of Campinas - Brazil
2MFR, MD, PhD, Researcher (Retired) Instituto de Saude SES/São Paulo, Brazil
3AMSC, MD, PhD, Professor of Epidemiology (Retired) University of Campinas, São Paulo, Brazil

*Corresponding Author: Marina Ferreira Rea, MFR, MD, PhD, Researcher (Retired) Instituto de Saude SES/São Paulo, Brazil.

Received: May 31, 2022; Published: June 24, 2022

Abstract

Iron deficiency anemia is a very common nutritional disorder among pregnant women and children. Although anemia is not identified as the primary cause of death, it is related to the impairment of physical and cognitive development in children and to weakness in the mechanism of immunity, thus increasing morbidity rates.  This article aims to discuss the time of umbilical cord clamping and anemia among children under six months of age, analyzing the possible relationships with socio-economic and demographic and biomedical conditions. This is a cohort, with a total study sample of 934 children, but we had losses during follow-up at 150 days of life, resulting in a sample of 592 children aged close to 5 months. Maintaining the parameters established by the study design, this number of children is sufficient to perform the proposed analyses. The variables considered in the study can be divided in variables that deal with socio-economic and demographic conditions, such as: age, schooling and maternal work, in addition to per capita family income. And biomedical variables such as: gestational age, type of pregnancy, birth weight, time of umbilical cord clamping, pre-gestational body mass index, maternal anemia, prenatal follow-up and breastfeeding. The development of the study followed the requirements of the committee standards in Pesquisa CEP/FCM/UNICAMP No. 198/2004).  Ducting as significant variables for risk of iron deficiency anemia for children under 5 months of age, gestational age less than 37 weeks, type of pregnancy, being the duo with the highest risk for the disease and birth weight less than 2500grams. The clamping time of the cord was not related to anemia because, in this study, the clamping of the cord of the delivered deliveries was early in 91.6% of the cases, presenting an average of 18.5seconds.  In this study, the mean time of umbilical cord clamping was very low and even though no association was observed with anemia among the infants studied, there is already evidence that guides changes in this practice.

Descriptors

  • Anemia, iron-deficiency
  • Delivery of care
  • Newborn
  • Epidemiology
  • Cord umbilical clamping

Keywords: Iron Deficiency Anemia; Children; Umbilical Cord Clamping

References

  1. Chopra A., et al. “Early versus delayed cord clamping in small for gestational age infants and iron stores at 3 months of age - a randomized controlled trial”. BMC Pediatric18 (2018): 234.
  2. Mercer JS., et al. “Effects of Delayed Cord Clamping on 4-Month Ferritin Levels, Brain Myelin Content, and Neurodevelopment: A Randomized Controlled Trial”. The Journal of Pediatrics 203 (2018): 266-272.e2.
  3. Steffen EL., et al. “Effect of late umbilical cord clamping on serum ferritin levels of children aged 0, 3 and 6 months of life”. Journal of the Adolfo Lutz Institute1 (2012): 160-165.
  4. GL Stained Glass. “TIMELY CLAMPING OF UMBILICAL CORD AND ITS REPERCUSSIONS ON NEONATAL HEMOGLOBIN CONCENTRATION”. SaBios1 (2018): 35-41.
  5. Grajeda R., et al. “Delayed clamping of the umbilical cord improves hematologic status of Guatemalan infants at 2mo of age”. American Journal Clinical Nutrition 65 (1997): 425-431.
  6. Word Health Organization. “Care of the Umbilical Cord: a review of the evidence”. Geneva, Switzerland; 1998b:11-12. WHO/RHTMSM/98.4.
  7. Mercer JS. “Current best evidence: a review of the literature on umbilical cord clamping”. Journal Midwifery Women Health 46 (2001): 402-414.
  8. Chaparro CM., et al. “Effect of timing of umbilical cord clamping on iron status in Mexican infants: a randomised controlled trial”. Lancet 367 (2006): 1997-2004.
  9. Van Rheenen P and Brabin BJ. “Late umbilical cord-clamping as an intervention for reducing iron deficiency anaemia in term infants in developing and industrialized countries: a systematic review”. Annals of tropical paediatrics 24 (2004): 3-16.
  10. Mercer J and Erickson-Owens D. “Delayed cord clamping increases infants ‘iron stores”. Lancet 367 (2006): 1956-1958.
  11. Oh W., et al. “The effects of placental transfusion on respiratory mechanics of normal term newborn infants”. Pediatrics 40 (1967): 6-12.
  12. Yao AC., et al. “Expiratory grunting in the lateclamped normal neonate”. Pediatrics 48 (1971): 865-870.
  13. Saigal S., et al. “Placental transfusion and hyperbilirubinemia in premature”. Pediatrics 49 (1972): 406-419.
  14. Hutton EK and Hassan ES. “Late vs early clamping of the umbilical cord in full-term neonates - systematic review and meta-analysis of controlled trials”. JAMA 297 (2007): 1241-1252.
  15. Mercer JS., et al. “Umbilical cord clamping: beliefs and practices of Amercian nurse-midwives”. Journal Midwifery Women Health 45 (2000): 58-66.
  16. Brazil, Ministry of Health. Prenatal Care: Technical Manual/preparation team: Janine Schirmer et al. - 3rd edition - Brasília: Health Policy Secretariat - SPS/Ministry of Health (2000).
  17. Matos LL., et al. “Late umbilical cord clamping: interference in the development of neonatal iron deficiency anemia and other benefits”. Brazilian Journal of Development, Curitiba8 (2021): 86135-86142.
  18. Novellino and Maria Salet Ferreira. “A study on Brazilian adolescent mothers. Physis”. Journal of Collective Health 1 (2011): 299-318.
  19. Brazilian Institute of Geography and Statistics (IBGE). National Basic Sanitation Survey 2017: water supply and sewage/IBGE, Population Coordination and Social Indicators. - Rio de Janeiro: IBGE (2020).

Citation

Citation: Marina Ferreira Rea., et al. “Iron Deficiency Anemia in Children Younger than Six Months and Time of Umbilical Cord Clamping. Anemia in 6 Months Old Infants and Delayed Clamping of the Umbilical Cord ". Acta Scientific Nutritional Health 6.7 (2022): 73-78.

Copyright

Copyright: © 2022 Marina Ferreira Rea., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.316

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue".
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US