Abstract

Anethum graveolens is a well-acknowledged and widely used culinary annual herb belongs to the family Apiaceae, commonly known as “dill”. The seeds of dill are stomachic, carminative, and diuretic. It comprises numerous bioactive compounds which are broadly exploited for different medicinal purposes. A. graveolens contain a specific odor due to the presence of essential oils. The plant extracts and oil have different activities such as antimicrobial, antioxidant, anti- hypercholesterolemic, anti-inflammatory, anti-diabetic, etc. The main aim of this review is to comprehend the importance, bioactivities and medicinal uses of A. graveolens and its secondary metabolites.

Keywords: Anethum Graveolens; Bioactivates; Antinociceptive; Secondary Metabolites; Plant Extracts

References

1. Bodeker G, and Ong CK. “WHO global atlas of traditional, complementary and alternative medicine, Volume 1”. World Health Organization (2005).
2. Heamalatha S., et al. “Pharmacognostical, pharmacological, investigation on Anethum graveolens Linn: A review”. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2.4 (2011): 564-574.
3. Hemphill I. “The Spice and Herb Bible”. Toronto, ON, Canada: Robert Rose (2006).
4. Ugulu I., et al. “The investigation and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey”. Journal of Medicinal Plants Research 5 (2009): 345-367.
5. Orhan IE., et al. “Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens (dill) samples cultivated under organic and conventional agricultural conditions”. Food and Chemical Toxicology 59 (2013): 96-103.
6. Sonigra P and Meena M. “Metabolic profile, bioactivities, and variations in the chemical constituents of essential oils of the Ferula genus (Apiaceae)”. Frontiers in Pharmacology 11 (2021): 608649.
7. Khare CP. “Encyclopedia of Indian Medicinal Plants: Rational Western Therapy, Ayurvedic and Other Traditional Usage, Botany”. Springer (2004).
8. Ravindran PN and Balachandran I. “Underutilized medicinal species-III”. Spice India 18.2 (2005): 16-24.
9. Bahramikia S and Yazdanparast R. “Antioxidant and free radical scavenging activities of different fractions of Anethum graveolens leaves using in vitro models”. Pharmacology OnLine 2 (2008): 219-233.
10. Kaur GJ and Arora DS. “Bioactive potential of Anethum graveolens, Foeniculum vulgare and Trachyspermum ammi belonging to the family Umbelliferae - Current status”. Journal of Medicinal Plants Research2 (2010): 087-094.
11. Malhotra SK and Vashishtha BB. “Response of Indian dill (Anethum sowa) and European dill (Anethum graveolens) varieties to different agro-techniques”. Indian Journal of Agricultural Science8 (2007): 519-522.
12. Jana S and Shekhawat GS. “Anethum graveolens: An Indian traditional medicinal herb and spice”. Pharmacognosy Reviews8 (2010): 179-184.
13. Mohammed FA., et al. “Protective role of medicinal herb Anethum graveolens (Dill) against various human diseases and metabolic disorders”. In: Plant and Human Health, Volume 3. Springer, Cham., (2019): 181-194.
14. Chen Y., et al. “Antifungal mechanism of essential oil from Anethum graveolens seeds against Candida albicans”. Journal of Medical Microbiology 62.8 (2013): 1175-1183.
15. Zeng H., et al. “In vitro and in vivo activities of essential oil from the seed of Anethum graveolens against Candida spp.”. Evidence-Based Complementary and Alternative Medicine (2011): 659704.
16. Ruangamnart A., et al. “Chemical compositions and antibacterial activity of essential oil from dill fruits (Anethum graveolens) cultivated in Thailand”. Mahidol University Journal of Pharmaceutical Sciences 42.3 (2015): 135-143.
17. Rabeh NM., et al. “Hepatoprotective effect of dill (Anethum graveolens) and fennel (Foeniculum vulgare) oil on hepatotoxic rats”. Pakistan Journal of Nutrition 13.6 (2014): 303-309.
18. Rezaee Asl M., et al. “Antinociceptive properties of hydro alcoholic extracts of Anethum graveolens (dill) seed and aerial parts in mice”. Journal of Clinical and Experimental Pharmacology 3 (2013): 122.
19. Chaubey MK. “Insecticidal activities of Anethum graveolens and Illicium verum Hook. f. essential oils against Sitophilus zeamais Motschulsky”. Revista de Ciencias Agrícolas 38.1: (2021): 38-49.
20. Al-Oqail MM and Farshori NN. “Antioxidant and anticancer efficacies of Anethum graveolens against human breast carcinoma cells through oxidative stress and caspase dependency”. BioMed Research International 2021 (2021): 5535570.
21. Nehdia IA., et al. “Chemical composition, oxidative stability and antiproliferative activity of Anethum graveolens (dill) seed hexane extract”. Grasasy Aceites 71.3 (2020): e374-e374.
22. Abas ASM and Elagib SM. “Antiparasitic activity of aqueous extract of Anethum graveolens against Entamoeba histolytica: in vitro and in vivo study”. Biocatalysis and Agricultural Biotechnology 34 (2021): 102026.
23. El Mansouri L., et al. “Phytochemical screening, antidepressant and analgesic effects of aqueous extract of Anethum graveolens from southeast of Morocco”. American Journal of Therapeutics 23.6 (2016): e1695-e1699.
24. Mahmoodi A., et al. “Chemical composition and antibacterial activity of essential oils and extracts from Rosmarinus officinalis, Zataria multiflora, Anethum graveolens and Eucalyptus globulus”. Global Veterinaria 9.1 (2012): 73-79.
25. Kazemi M. “Chemical composition and antimicrobial, antioxidant activities and anti-inflammatory potential of Achillea millefolium, Anethum graveolens L., and Carum copticum L. essential oils”. Journal of Herbal Medicine 5.4 (2015): 217-222.
26. Kalangi SK., et al. “Biocompatible silver nanoparticles reduced from Anethum graveolens leaf extract augments the antileishmanial efficacy of miltefosine”. Experimental Parasitology 170 (2016): 184-192.
27. Makhfian M., et al. “Anti-quorum sensing effetcs of ethanolic crude extract of Anethum graveolens L”. Journal of Essential Oil-Bearing Plants 18.3 (2015): 687-696.
28. Al-Sheddi ES., et al. “Evaluation of cytotoxicity, cell cycle arrest and apoptosis induced by Anethum graveolens essential oil in human hepatocellular carcinoma cell line”. Saudi Pharmaceutical Journal 27.7 (2019): 1053-1060.
29. Khani A and Basavand F. “Chemical composition and insecticide activity of essential oil from dill seeds”. International Journal of Agriculture3 (2013): 489.
30. Ebadollahi A., et al. “Insecticidal activity of essential oils of five aromatic plants against Callosobruchus maculatus (Coleoptera: Bruchidae) under laboratory conditions”. Journal of Essential Oil Bearing Plants 15.2 (2012): 256-262.
31. Goodarzi MT., et al. “The role of Anethum graveolens (Dill) in the management of diabetes”. Journal of Tropical Medicine 2016 (2016).
32. Mousavi SM., et al. “The effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials”. Critical Reviews in Food Science and Nutrition 2021 (2021): 1-12.
33. Yadav G and Meena M. “Bioprospecting of endophytes in medicinal plants of Thar Desert: An attractive resource for biopharmaceuticals”. Biotechnology Reports 30 (2021): e00629.
34. Mohammad IH. “Use of Anethum graveolens in the management of patients with irritable bowel syndrome”. Mustansiriya Medical Journal1 (2012): 94-98.

Citation

Citation: Mukesh Meena., et al. “A Review on Pharmaceutical and Medicinal Importance of Anethum Graveolens L". Acta Scientific Nutritional Health 6.7 (2022): 23-28.

Copyright

Copyright: © 2022 Mukesh Meena., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.