Wondyefraw Mekonen*

Department of Physiology, College of Health Sciences (CHS), Addis Ababa University, Ethiopia

*Corresponding Author: Wondyefraw Mekonen, Department of Physiology, College of Health Sciences (CHS), Addis Ababa University, Ethiopia.

Received: April 11, 2022; Published: May 25, 2022

Abstract

Controversy exists in literatures concerning the effect of diet-alone or diet-with exercise in altering blood high-density lipoprotein-Cholesterol (HDL-C) concentration. This case study has assessed the influence of consuming high-CHO and high-fat diet in altering blood HDL-C alone or in combination with exercise. A healthy active subject, 29 years and 78 kg had a basal HDL-C level of 50.9 mg/dl with normal-balanced diet. 1. During diet-alone trial, the subject consumed a high-CHO diet (70% CHO, 18% fat, 12% protein) for 1-month and his HDL-C level was 36.3 mg/dl. After 7-days gap, he took high-fat diet (20% CHO, 68% fat, 12% protein) for 1-month and his HDL-C was raised to 71.4 mg/dl. 2. During diet with exercise trial, the subject took similar (i.e., high-CHO and high fat) diet and additionally performed an intensive (85% HRmax, 30 min), and moderate excise (50% HRmax, 90 min) tests with 7 days interval. Results indicated that high-CHO intake alone or with exercise, depressed blood HDL-C to the same degree (by about 28%), but to the contrary, intake of high-fat diet elevated HDL-C (by about 40%) compared to the basal diet. Exercise did not influence HDL-C concentration different from the dietary effect alone. This case report primarily indicates a greater sensitivity of HDL-C to diet than physical exercise in optimizing blood HDL-level. A cohort study that includes gender is necessary to reach to a reasonable conclusion.

Keywords: Diet; HDL-C; Exercise; High-Fat; Diet Alone

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Citation

Citation: Wondyefraw Mekonen. “Is it “Diet Alone” or “Diet-with-Exercise” that Primarily Influence Blood HDL-C Concentration? a Case Study". Acta Scientific Nutritional Health 6.6 (2022): 68-71.

Copyright

Copyright: © 2022 Wondyefraw Mekonen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.