Bacteroidetes Help Hosts Harvest More Energy from High Fiber Diets
Xue bin1, Pingru Liu1 and Gang Wu2,3*
1School of Engineering, Guangzhou College of Technology and Business,
2Department of Food, Wine, and Molecular Bioscience, Lincoln University,
Christchurch, New Zealand
3Riddet Institute, Palmerston North, New Zealand
*Corresponding Author: Gang Wu, Department of Food, Wine, and Molecular Bioscience, Lincoln University, Christchurch, New Zealand and Riddet Institute, Palmerston North, New Zealand.
January 31, 2022; Published: February 21, 2022
Obesity has been associated with imbalance of gut microbiota. The objective of this study was to investigate the role of gut microbiota in host’s harvesting energy. During the period of 8 weeks’ feeding of the high-soybean-fiber (HSF) diet or the high-fructooligosaccharide (HFOS) diet, the rats’ body weight (BW), gut microbiota composition, short chain fatty acids (SCFAs) in feces, plasma lipopolysaccharide (LPS) and leptin were measured at week 0, 4 and 8. The results presented high dietary fibers (HDFs) can up-regulate the abundance of Bacteroidetes in rats’ gut. Since Bacteroidetes can hydrolyze complex carbohydrates to release energy, such as SCFAs, lean rats, more Bacteroidetes growing in their gut, gained more body weight than the obese ones when they both consumed the same HDF diets. The fluctuations of plasma LPS and leptin individually kept consistent with that of the abundance of Gram-negative bacteria in feces and rats’ BW gain. Hence, Bacteroidetes in gut is the key one to help hosts harvest more energy from HDFs diet.
Keywords: Obesity; Gut Microbiota; Short Chain Fatty Acids; Lipopolysaccharide; Leptin
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