Effects of Selenium Mineral on Health
Rabia Melda Karaağaç, Çağla Pınarli and Fatih Tarlak*
Faculty of Health Sciences, Department of Nutrition and Dietetics, İstanbul Gedik University, İstanbul, Turkey
*Corresponding Author: Fatih Tarlak, Faculty of Health Sciences, Department of Nutrition and Dietetics, İstanbul, İstanbul Gedik University, Turkey.
November 22, 2021; Published: December 20, 2021
Selenium (Se), discovered by Brezilius and Gahn in 1817, is a trace element that is known as a cofactor of many enzymes in our body and has an antioxidant function. It is found in nature and organisms in organic and/or inorganic forms. Se is an important component of selenoproteins that play a role in many biological functions such as antioxidant defense, formation of thyroid hormones, DNA synthesis, fertility, and reproduction. The most important sources of Se are brazil nuts, offal, and fish. Adults should consume 55 micrograms per day. Se toxicity can occur if Se has taken into the body more than necessary. The most common clinical symptoms of Se toxicity are hair loss and split nails. Adults should consume no more than 400 micrograms of Se per day. Se shortage is more common in areas where the soil contains little Se. As a result of deficiency, Keshan and Kashin-Beck diseases occur in people. Se is a mineral that has been linked to chronic illnesses like cancer and cardiovascular disease. There is also a relationship between selenium and gut microbiata. This review aims to discuss the Se mineral from a clinical and metabolic point of view.
KeywordsSe; Mineral; Antioxidant; Selenoprotein; Thyroid; Cardiovascular Disease; Cancer; Enzymes
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