Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 5 Issue 11

Type 2 Diabetes, Physical Activity and Risk of Mild Cognitive Impairment and Dementia in Community Dwelling Old Adults

Eymundsdottir H1*, Chang M1, Geirsdottir OG2, Jonsson PV1,3,4, Gudnason V3,5, Launer L6 and Ramel A2

1The Icelandic Gerontological Research Center, the National University Hospital of Iceland, Reykjavik, Iceland

2Faculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland

3Faculty of Medicine, University of Iceland, Iceland

4Department of Geriatrics, the National University Hospital of Iceland, Reykjavik, Iceland

5Icelandic Heart Association, Kopavogur, Iceland

6Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA

*Corresponding Author: : Eymundsdottir H, The Icelandic Gerontological Research Center, the National University Hospital of Iceland, Reykjavik, Iceland.

Received: October 05, 2021; Published: October 21, 2021

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Abstract

Introduction: We aim to investigate the longitudinal associations between level of physical activity (PA) and the risk of mild cognitive impairment (MCI) and dementia among type 2 diabetes (T2D) and pre-diabetes (PD) participants who are cognitively normal at study entry.

Methods: We used data from the Age-Gene/Environment-Susceptibility-Reykjavik-Study (65-96 years). From the original sample, 3001 participants with a complete evaluation of T2D, MCI and dementia were included in this analysis.

Results: During follow-up (5.2 years), 8.5% (n = 256) developed MCI and 3.7% (n = 111) developed dementia. T2D participants had an increased risk for MCI (OR = 1.632, P = 0.021) and both PD and T2D individuals had increased risk for dementia (OR = 1.947, P = 0.003 and OR=2.101, P = 0.026). PA was associated with lower dementia risk in normal participants only (OR = 0.611, P = 0.019).

Discussion: Older adults with PD/T2D had low level of PA and higher risk of declining cognitive function.

Keywords: Type 2 Diabetes; Mild Cognitive Impairment; Dementia; Physical Activity; Glucose Regulations

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Citation

Citation: Eymundsdottir H., et al. “Type 2 Diabetes, Physical Activity and Risk of Mild Cognitive Impairment and Dementia in Community Dwelling Old Adults".Acta Scientific Nutritional Health 5.11 (2021): 59-66.




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