A Literature Review of Gelatin: Past, Present and Future in Drug Delivery
Ambujakshi Manjunatha Vinayaka1*, Harsha Madakaripura Dasegowda2 and Priyanka Raj3
1Bapuji Dental College and Hospital, Davanagere, Karnataka, India
2Post Graduate Student, Bapuji Dental College and hospital, Davanagere, Karnataka, India
3Raja Rajeswari Dental College and Hospital, Bengaluru, Karnataka, India
*Corresponding Author: Ambujakshi Manjunatha Vinayaka, Bapuji Dental College and Hospital, Davanagere, Karnataka, India.
September 06, 2021; Published: September 18, 2021
Hydrogels are liquid-absorbing polymer networks that can absorb any liquid, including biological fluids. The hydrogels are made up of natural polymers and their derivatives, as well as synthetic polymers. The crosslinking of either synthesised polymers starting from monomers or already established polymers creates the networks that make up hydrogels. Crosslinking can occur either physically, involving secondary intermolecular interactions, or chemically, involving the formation of a covalent connection between polymeric chains. Gelatins are protein polymers that are derived from natural sources. Gelatin is one of the most common biopolymers used to make hydrogels. Other than hydrogels, gelatin has a wide range of applications. Hydrogels, their properties and synthesis mechanisms, as well as their application in biomedicine and gelatin chemistry and application, are discussed in this review. Gelatin-based hydrogels could be used in drug delivery, bioink, transdermal therapy, wound healing, and tissue repair due to their nonimmunogenicity, nontoxicity, low cost, and great availability. On the condition that cost-effective, sustainable technologies for converting gelatin into valuable bioproducts exist or are developed, gelatin beneficiation can result in their sustainable conversion into high-value biomaterials.
Keywords:Characteristics; Gelatin; Drug Delivery
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