Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 5 Issue 7

Effect of Ground Flaxseed Intake on Lipidic Profile in Subjects with Dyslipidemic with and without Pharmacotherapy

M Paz Beyer1*, Camila Escala1, Javiera Gómez1, Javiera González1 and Ximena Palma2

1Student of Nutrition and Dietitics, Universidad de Valparaíso, Chile
2Faculty of Nutrition and Dietitics, Universidad de Valparaíso, Chile

*Corresponding Author: M Paz Beyer, Student of Nutrition and Dietitics, Universidad de Valparaíso, Chile.

Received: April 23, 2021; Published: June 07, 2021


Background: Dyslipidemia corresponds to a number of alterations of blood lipids concentrations that is associated with health risks. Diets high in fat, family background, among others are risk factors. One way to correct lipid alterations would be to consume dietary fiber like the one present in ground flaxseed, which could contribute to the improvement of cholesterol and triglycerides levels.

General Objective: To determine the effect of daily consumption of ground flaxseed on the lipid profile of 10 dyslipidemic subjects diagnosed with a follow up of 1 month.

Methods: Participants in this study were adults, age 40-70 years old. Subjects consumed 15 g of ground flax in 200 ml of water with their lunch. Blood lipid profile tests were performed before and after consumption for one month. Data was analyzed using an individual delta for each lipid profile and was compared using analysis of variance (ANOVA). To evaluate the difference in food intake the averages of each variable were compared using T-Student test.

Results: There was a statistically significant decrease in LDL cholesterol in all the participants from 184 ± 28,38 mg/dL to 139 ± 29,02 mg/dL during the 1-month follow up. The changes in levels of total cholesterol, LDL and blood triglycerides were statistically significant.

Conclusion: The daily intake of flaxseed with a meal is associated with improved levels of LDL.

Keywords:Dyslipidemia; Soluble Fiber; Lipid Profile; Ground Flax; Cholesterol


  1. Ministerio de Salud, Chile. “Normas Técnicas Dislipidemias”. (2017).
  2. Miguel S., et al. “Dislipidemias”. ACIMED 20.6 (2009): 265-273.
  3. S. Departament of Health and Human Services. “ATP III Guidelines At-A-Glance Quick Desk Reference” (2017).
  4. C Carvajal. “Lipoproteins: metabolism and atherogenic lipoproteins., of Costa Rican Legal Medicine” (2017).
  5. Ministerio de Salud, Chile. “Dislipidemias” (2000).
  6. Octavio M., et al. “Cholesterol : Biological function and medical implications”. Revista Mexicana De Ciencias Farmacéuticas 2 (2012).
  7. Angeles C. “Manual de Nutrición y Dietética, Fibra Dietética”. Universidad Complutense de Madrid. (2017).
  8. Juliet G. “Dietary fiber”. ILSI (2017).
  9. Fernando F., et al. “Lyxse as a source of bioactive compounds for food processing”. Agro sur2 (2008).
  10. Shim Y., et al. “Flaxseed (Linum usitatissimum L.) bioactive compounds and peptide nomenclature: A review”. Journal Trends in Food Science and Technology1 (2014).
  11. Kátia C., et al. “Efecto de la semilla de linaza en el crecimiento de ratas wistar”. Revista Chilena de Nutricion 4 (2008).
  12. Squire A. et al. “Dietary fiber”. Hospital Nutrition 21 (2006): 61-72.
  13. Linda M. “Flaxseed- ancient grain rich in health and cooking benefits”. Healthy Flax (2015).
  14. S Dodin. “The Effects of Flaxseed Dietary Supplement on Lipid Profile, Bone Mineral Density, and Symptoms in Menopausal Women: A Randomized, Double-Blind, Wheat Germ Placebo-Controlled Clinical Trial”. Journal of Clinical Endocrinology and Metabolism3 (2005): 1390-1397.
  15. W Ratnayake. “ Chemical and nutritional studies of flaxseed (variety Linott) in rats de The Journal of Nutritional Biochemistry”. Journal of Nutritional Biochemistry5 (1992).
  16. A Catalina. “Efecto del consumo de linaza en el perfil lipídico, el control del cáncer y como terapia de reemplazo hormonal en la menopausia: una revisión sistemática de ensayos clínicos aleatorizados”. Perspectivas en Nutrición Humana 1 (2011): 73-91.
  17. Marambio I. “Exámenes de laboratorio ¿Qué es el perfil lipídico?” Clínica Alemana (2017).
  18. Lisa B. “Cholesterol-lowering effects of dietary fiber: a meta-analysis”. The American Journal of Clinical Nutrition1 (1999): 30-42.
  19. Aura M., et al. “Efecto de la avena y/o lovastatina sobre el perfil lipídico en pacientes dislipidémicos del hospital de Tunjuelito, Bogotá”. Revista U.D.C.A Actualidad and Divulgación Científica 2 (2013): 319-326.
  20. Ruiz F. “Consumo de avena (Avena sativa) y prevención primaria de la dislipidemia en adultos sin restricción dietética”. Atención Familiar 2 (2011).
  21. Sastre G. “Fibra y prebióticos: conceptos y perspectivas”. Revista Gastroenterología y Hepatología 26 (2003): 6-12.
  22. Fernández C., et al. “La fibra dietética en la prevención del riesgo cardiovascular”. Revista Nutrición Clínica y Dietética Hospitalaria2 (2010): 4-12.
  23. Octavio M., et al. “Colesterol: Función biológica e implicaciones médicas, de Revista mexicana de ciencias farmacéuticas”. Revista Mexicana De Ciencias Farmacéuticas2 (2012).
  24. Valenzuela A., et al. ” Fitoesteroles y fitoestanoles: aliados naturales para la protección de la salud cardiovascular”. Revista Chilena de Nutrición 31 (2004): 161-169.
  25. Muñoz A., et al. “Fitoesteroles y fitoestanoles: Propiedades saludable”. Revista Horizonte Médico2 (2011).


Citation: M Paz Beyer., et al. “Effect of Ground Flaxseed Intake on Lipidic Profile in Subjects with Dyslipidemic with and without Pharmacotherapy".Acta Scientific Nutritional Health 5.7 (2021): 15-21.


Copyright: © 2021 M Paz Beyer., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.316

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US