Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 4 Issue 11

A Neurocommunication Model between the Brain and Liver Regarding Glucose Production and Secretion in Early Morning Using GH-Method: Math-Physical Medicine (No. 324)

Gerald C Hsu*

eclaireMD Foundation, USA

*Corresponding Author: Gerald C Hsu, eclaireMD Foundation, USA.

Received: September 30, 2020; Published: October 16, 2020



  This article address the author’s hypothesis on the neurocommunication model existing between the brain and liver regarding production and glucose secretion in the early morning. This is based on the observation of the difference between glucose at wake up moment in the morning for the fasting plasma glucose (FPG), and glucose at the first bite of breakfast for the glucose at 0-minute or “open glucose” of postprandial plasma glucose (PPG). All of the eight identified glucoses of breakfast PPG are higher than the eight glucoses at time of wake up by a difference of an average of 8 mg/dL. The value difference using Method B of CGM sensor glucoses during the COVID-19 period offers the most accurate picture and credible glucose difference of 8 mg/dL between his FPG at wake-up moment and PPG at the first bite of breakfast. The author believes that the brain senses when a person wakes up due to different kinds of stimuli from many sources, including eye, environment and even internal organs, which will alert the body to be in “active” mode requiring “energy” through glucose. Even though the person has not eaten anything or is not actively moving, the brain issues a marching order to the liver to produce or release glucose for the body to use in the forthcoming day. This hypothesis can currently explain why his glucose of eating his breakfast is ~8 mg/dL higher than his FPG at wakeup.

Keywords: Neurocommunication Model; Brain; Liver; Glucose Production; GH-Method



  1. Hsu Gerald C. “Biomedical research methodology based on GH-Method: math-physical medicine (No. 310)”. eclaireMD Foundation, USA (2020).
  2. Hsu Gerald C. “Self-recovery of pancreatic beta cell’s insulin secretion based on annualized fasting plasma glucose, baseline postprandial plasma glucose, and baseline daily glucose data using GH-Method: math-physical medicine (No. 297)”. eclaireMD Foundation, USA (2020).
  3. Hsu Gerald C. “Diabetes control and metabolism maintenance during COVID-19 period in comparison to three other periods using GH-Method: math-physical medicine (No.288)”. eclaireMD Foundation, USA (2020).
  4. Hsu Gerald C. “Comparison study of PPG characteristics from candlestick model using GH-Method: Math-Physical Medicine (No. 261)”. eclaireMD Foundation, USA (2020).


Citation: Gerald C Hsu. “A Neurocommunication Model between the Brain and Liver Regarding Glucose Production and Secretion in Early Morning Using GH-Method: Math-Physical Medicine (No. 324)".Acta Scientific Nutritional Health 4.11 (2020): 41-45.


Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.316

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