Abstract

  Secretary IgA is a key element of intestinal immunity. Low levels of secretory IgA (SIgA) and development of allergy in infants were often reported, but it is not in adults. Saliva and serum were simultaneously analyzed from 20 adult patients with Cedar pollinosis aged 22-53 years and 22 non-allergic control adults aged 25-65 years. The mean salivary level of SIgA for JCP patients was significantly lower than the value for control subjects (58.1 ± 8.8 ug/ml vs. 68.6 ± 12.1 ug/ml). On the contrary, Cedar pollen specific IgE in the serum was 11.5 U_A/ml, 4.05, 23.1, respectively (median, 25^th-75^th percentile) in pollinosis group, while it was <0.34 UA/ml (detection limit) in control group. Low levels of salivary SIgA in adults was associated with increased allergic manifestations.

Keywords: Allergic Pollinosis; Japanese Cedar Pollen; Saliva; Secretory IgA, Specific IgE Antibodies

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Citation

Citation: Hideyo Yamaguchi., et al. “The Relationship between Allergic Pollinosis and Low Salivary Levels of Secretory IgA in Adults".Acta Scientific Nutritional Health 4.11 (2020): 16-21.

Copyright

Copyright: © 2020 Hideyo Yamaguchi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.