Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 4 Issue 11

The Relationship between Allergic Pollinosis and Low Salivary Levels of Secretory IgA in Adults

Tetsuro Yamamoto1, Tadao Enomoto2, Akira Tsuda3, Hisayoshi Okamura4, Tatsuya Honda1, Shaw Watanabe5 and Hideyo Yamaguchi1*

1Research Center, TTC Co., Ltd., Tokyo, Japan
2NPO Japan Health Promotion Supporting Network, Wakayama, Japan
3Department of Psychology, Kurume University, Kurume, Japan
4Cognitive and Molecular Institute of Brain Diseases Kurume University, Kurume, Japan
5LifeScience Promoting Association, Tokyo University of Agriculture, Tokyo, Japan

*Corresponding Author: Hideyo Yamaguchi, Research Center, TTC Co., Ltd., Tokyo, Japan.

Received: September 23, 2020; Published: October 07, 2020



  Secretary IgA is a key element of intestinal immunity. Low levels of secretory IgA (SIgA) and development of allergy in infants were often reported, but it is not in adults. Saliva and serum were simultaneously analyzed from 20 adult patients with Cedar pollinosis aged 22-53 years and 22 non-allergic control adults aged 25-65 years. The mean salivary level of SIgA for JCP patients was significantly lower than the value for control subjects (58.1 ± 8.8 ug/ml vs. 68.6 ± 12.1 ug/ml). On the contrary, Cedar pollen specific IgE in the serum was 11.5 UA/ml, 4.05, 23.1, respectively (median, 25th-75th percentile) in pollinosis group, while it was <0.34 UA/ml (detection limit) in control group. Low levels of salivary SIgA in adults was associated with increased allergic manifestations.

Keywords: Allergic Pollinosis; Japanese Cedar Pollen; Saliva; Secretory IgA, Specific IgE Antibodies



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Citation: Hideyo Yamaguchi., et al. “The Relationship between Allergic Pollinosis and Low Salivary Levels of Secretory IgA in Adults".Acta Scientific Nutritional Health 4.11 (2020): 16-21.


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