Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Research Article Volume 4 Issue 4

Role of Next Generation Sequencing (NGS) in Searching for Promising Lactic Acid Strains Used as Animal Probiotic

Bushra Urooj1,2, Maria Sohail1, Allah Nawaz Khan2, Muhammad Aqeel1, Dur Shehwar2, Abdul Manan1 and Shakira Ghazanfar1*

11National Institute of Genomics and Agriculture Biotechnology (NIGAB), National Agriculture Research Centre, Park Road, Islamabad, Pakistan
2Department of Life Sciences, Abasyn University Islamabad campus Park road, Islamabad, Pakistan

*Corresponding Author: Shakira Ghazanfar, National Institute of Genomics and Agriculture Biotechnology (NIGAB), National Agricultural Research Centre, Park Road, Islamabad, Pakistan.

Received: February 21, 2020; Published: April 07, 2020


  Next generation sequencing (NGS) has revolutionized the research related to the study of animal gut. Scientists point out, that little information has been investigated regarding the link between the animal health production and ruminal gut ecosystem. Hence, we review the advance progress in studying the host-microbial interactions. Scientists have developed/used new molecular approaches and computational techniques for metagenomic and whole genome sequencing analysis to search the promising probiotic strains which has the capability to improve milk yield. For the preparation of the unique probiotic product researcher should work on the isolation of microbial flora to conventional microbial molecular techniques merged with complex algorithms of computational efficiency for whole genome sequence analysis. Ruminal-gut microbiota is considered as a major source of unique probiotic bacterial strains. Probiotics are “live microorganisms which when administered in adequate amounts confer a health benefit on the host”.

Keywords: Next Generation Sequencing (NGS); Lactic Acid Bacteria (LAB); Animal Probiotic



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Citation: Shakira Ghazanfar., et al. “Role of Next Generation Sequencing (NGS) in Searching for Promising Lactic Acid Strains Used as Animal Probiotic". Acta Scientific Nutritional Health 4.4 (2020): 179-183.


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