Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Short Communication Volume 4 Issue 4

Could Antihistamines Help in the Treatment and Spread of COVID-19 Via Re-Modulating Cytokines and by Reducing Sneezing?

Suna Aydin1 and Suleyman Aydin2*

1Department of Cardiovascular Surgery, Elazig Fethi Sekin City Hospital, Health Science University, Elazig Campus, Turkey
2Department of Medical Biochemistry and Clinical Biochemistry, Medical School, Firat University, Turkey

*Corresponding Author: Suleyman Aydin, Department of Medical Biochemistry and Clinical Biochemistry, (Firat Hormones Research Group), Medical School, Firat University, Turkey.

Received: March 20, 2020; Published: March 27, 2020

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  Coronaviruses are a large family of viruses [1]. The latest member of this family is termed the SARS-Cov-2 which causes COVID-19 [2]. Outbreaks of SARS-Cov-2 are now pandemic, given the toll of infections worldwide and the Covid-19 associated death rate [3]. All governments have been taken by surprise and have difficulty in knowing what to do to control COVID-19. No vaccine is currently available against the virus.

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References

  1. Jonsdottir HR and Dijkman R. “Coronaviruses and the human airway: a universal system for virus-host interaction studies”. Virology Journal 13 (2016): 24.
  2. Cascella M., et al. “Features, Evaluation and Treatment Coronavirus (COVID-19)” (2020).
  3. Jones DS. “History in a Crisis - Lessons for Covid-19”. The New England Journal of Medicine (2020).
  4. Falus A and Merétey K. “Histamine: an early messenger in inflammatory and immune reactions”. Immunology Today 13 (1992): 154.
  5. Wu NZ and Baldwin AL. “Transient venular permeability increase and endothelial gap formation induced by histamine”. American Journal of Physiology 262 (1992): H1238.
  6. Sirois J., et al. “Importance of histamine in the cytokine network in the lung through H2 and H3 receptors: stimulation of IL-10 production”. Journal of Immunology 164 (2000): 2964-2970.
  7. Lagier B., et al. “Different modulation by histamine of IL-4 and interferon-γ (IFN-γ) release according to the phenotype of human Th0, Th1 and Th2 clones”. Clinical and Experimental Immunology 108 (1997): 545.
  8. Krouwels FH., et al. “Histamine affects interleukin-4, interleukin-5, and interferon-γ production by human T cell clones from the airways and blood”. American Journal of Respiratory Cell and Molecular Biology 18 (1998): 721.
  9. Delneste Y., et al. “Histamine induces IL-6 production by human endothelial cells”. Clinical and Experimental Immunology 98 (1994): 344.
  10. Jeannin P., et al. “Histamine induces interleukin-8 secretion by endothelial cells”. Blood 84 (1998): 2229.
  11. Borish L. “IL-10: evolving concepts”. The Journal of Allergy and Clinical Immunology 101 (1998): 293.
  12. Fiorentino DF., et al. “IL-10 inhibits cytokine production by activated macrophages”. Journal of Immunology 147 (1991): 3815.
  13. Fiorentino DF., et al. “IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells”. Journal of Immunology 146 (1991): 3444.
  14. Shirley DW., et al. “The therapeutic versatility of antihistamines: A comprehensive review”. Nurse practitioner 45 (2020): 8-21.
  15. https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---3-march-2020
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Citation

Citation: Suna Aydin and Suleyman Aydin. “Could Antihistamines Help in the Treatment and Spread of COVID-19 Via Re-Modulating Cytokines and by Reducing Sneezing?". Acta Scientific Nutritional Health 4.4 (2020): 172-173.




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