Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Short Communication Volume 4 Issue 1

Gut Microbiome and Nutrition

Pratik Pokharel*

European Public Health, School of Advanced Studies in Public Health (EHESP), France

*Corresponding Author: Pratik Pokharel, European Public Health, School of Advanced Studies in Public Health (EHESP), France.

Received: November 21, 2019; Published: December 11, 2019


  The organisms present in the digestive tract of humans surpass the human cells by almost 10 times and are collectively known as gut microbiome [1]. This microbiome may be considered as our other genome which when interacts with environmental factors can have a greater role than the human genome in obesity and disease development [2,3]. Profound changes in gut microbes’ mass have been reported in studies related to obesity indicating the microbiome involvement in the pathogenesis of obesity [3]. Gut microbes perform many specific functions in the human body. Synthesis of essential and non-essential amino acids, production of vitamins and biotransformation of bile are carried out by gut bacteria. Besides, the microbiome performs metabolism of polysaccharides, resistant starch, and other substances that skip digestion [1].



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  3. Le Chatelier E., et al. “Richness of human gut microbiome correlates with metabolic markers”. Nature 500.7464 (2013): 541-546. 
  4. Yadav M., et al. “A review of metabolic potential of human gut microbiome in human nutrition”. Archives of Microbiology 200.2 (2018): 203-217.
  5. Valdes AM., et al. “Role of the gut microbiota in nutrition and health”. BMJ 361 (2018): 36-44. 
  6. West CE., et al. “The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies”. The Journal of Allergy and Clinical Immunology 135.1 (2015): 3-13. 
  7. Hills RD., et al. “Gut Microbiome: Profound Implications for Diet and Disease”. Nutrients 11. (2019): 1613. 
  8. O’Keefe SJD., et al. “Fat, fibre and cancer risk in African Americans and rural Africans”. Nature Communications 6 (2015). 
  9. Brusaferro A., et al. “Is It Time to Use Probiotics to Prevent or Treat Obesity?” Nutrients 10.11 (2018): 1-14. 
  10. Wischmeyer PE., et al. “Role of the microbiome, probiotics, and ‘dysbiosis therapy’ in critical illness”. Current Opinion on Critical Care 22.4 (2016): 347-353. 
  11. Deehan EC and Walter J. “The Fiber Gap and the Disappearing Gut Microbiome: Implications for Human Nutrition”. Trends in Endocrinology and Metabolism 27.5 (2016): 239-242.


Citation: Pratik Pokharel. “Gut Microbiome and Nutrition".Acta Scientific Nutritional Health 4.1 (2020): 86-87.


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