Avinash Shankar¹*, Amresh Shankar² and Anuradha Shankar³

¹Chairman, National Institute of Health and Research, Institute of Applied Endocrinology, Bihar, India
²Centre For Endocrinology and Metabolism, Aarogyam Punarjeevan, Patna, India
³Director, Centre for Indigenous Medicine and Research, Bihar, India

*Corresponding Author: Avinash Shankar, Chairman, National Institute of Health and Research, Institute of Applied Endocrinology, Bihar, India.

Received: June 04, 2018; Published: July 11, 2018

Citation: Avinash Shankar., et al.“Effect of Initial Dietary Dose on Therapeutic Response and Quality of Life in Diabetes Mellitus”. Acta Scientific Nutritional Health 2.8 (2018).

Abstract

Introduction: Progressively increasing prevalence of Diabetes mellitus in India for which India is known as World Diabetic capital, is solely due to increasing non-nutrients in dietary constituents which alters body metabolism by affecting hepatic, pancreatic and incretin biokinetics adjunct with stress due to changed life style

 In spite of modalities for early detection, diagnosis and advancement in therapeutics, quality of life remain at stake and most encumbrance.

Objective of Study: To ascertain the effect of low caloric diet as initial diet on therapeutic outcome of diabetes mellitus.

Material and Method: 1000 patients of diabetes mellitus attending Centre for Endocrinology and Metabolism, Aarogyam punarjeevan, Ara Garden Road, Jagdeopath, Patna 14 and Institute of applied endocrinology, National Institute of Health and Research, Warisaliganj (Nawada) Bihar been considered for the proposed study.

 After due confirmation of their diabetic status and basic haemato-hepato-renal parameters patients were divided in to two equal group and one group were advocated < 100 calories diet while other more than 100 calories, with Oral hypoglycaemics to control blood sugar < 200 mg.

Result: The present study affirm that initial diet of < 100 calories prompt optimal incretin function and ensure blood sugar bioregulation, as this ensure optimal insulin secretion and insulin receptor sensitivity, thus attain sustained and progressive glycaemic control without any drug adversity, as no patients of this group shows post prandial blood sugar rise > 60 mg% and 165 (33%) patient show post prandial blood sugar even less than fasting blood sugar. While other group majority patients show post prandial blood sugar surge > 60 mg.

Conclusion: Hence optimal initial diet (< 100 calories) ensure better diabetes mellitus control and checks diabetic sequel.

Keywords: Diabetes Mellitus; Non-Nutrients; Hepatic; Pancreatic; Incretin; Insulin Receptor; Post Prandial Blood Sugar; Glycaemic Control

Copyright: © 2018 Avinash Shankar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.