Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 5 Issue 11

Umbilical Cord Index and Placental Intervillous Thrombi: Implications for Clinical Management

Tony Ighile1, Shona McKenna1, Queen Mudau1 and Paul H Hartel2*

1Atlantic Technological University, Sligo, Ireland
2Sligo University Hospital, Sligo, Ireland

*Corresponding Author: Paul H Hartel, Sligo University Hospital, Sligo, Ireland.

Received: October 10, 2023; Published: November 06, 2023

Abstract

In order to evaluate the association of placental pathology findings with umbilical cord index, we reviewed clinical and pathologic findings from 40 placentas. We found that umbilical cord index is associated with placental intervillous thrombi. Intervillous thrombi showed increased prevalence in cases with umbilical cord hypocoiling (83%; 5/6) vs. hypercoiling (50%; 3/6) or normal coiling (26%; 6/23). Other clinical and pathologic parameters showed no differences by umbilical cord index. Intervillous placental thrombi have been shown to be of maternal origin and have classical potential etiologies such as hypercoagulability, including maternal thrombophilias. Therefore, early sonographic identification of abnormally coiled umbilical cords, particularly hypocoiled cords, may serve as a marker for maternal screening of thrombotic risk.

Keywords: Umbilical Cord Index; Intervillous Thrombus; Coagulopathy; Thrombophilia; Fetal Ultrasound

References

  1. Cromi A., et al. “Sonographic atypical vascular coiling of the umbilical cord”. Prenatal Diagnosis 1 (2005): 1-6.
  2. Jessop, F.A., et al. “Umbilical cord coiling: clinical outcomes in an unselected population and systematic review”. Virchows Arch 464 (2014): 105-112.
  3. Patil N.S., et al. “Umbilical cord coiling index and perinatal outcome”. Journal of Clinical and Diagnostic Research 8 (2013): 1675-1677.
  4. Pergialiotis V., et al. “Umbilical cord coiling index for the prediction of adverse pregnancy outcomes: a meta-analysis and sequential analysis”.  Journal of Maternal-Fetal and Neonatal Medicine 23 (2020):  4022-4029.
  5. Predanic M., et al. “Ultrasound evaluation of abnormal umbilical cord coiling in second trimester of gestation in association with adverse pregnancy outcome”. American Journal of Obstetrics and Gynecology 2 (2005): 387-394.
  6. de Laat M.W., et al. “The umbilical coiling index, a review of the literature”. Journal of Maternal-Fetal and Neonatal Medicine 2 (2005): 93-100.
  7. Chitra T., et al. “Umbilical coiling index as a marker of perinatal outcome: an analytical study”. Obstetrics and Gynecology International (2012): 2012-2136.
  8. Sukhanova M., et al. “Maternal vs Fetal Origin of Placental Intervillous Thrombi”. American Journal of Clinical Pathology 3 (2022): 365-373.
  9. Najafi L., et al. “The association of umbilical coiling and angiogenesis markers: Impact assessment of gestational diabetes”. Placenta 129 (2022): 70-76.
  10. Hammad IA., et al. “Umbilical Cord Abnormalities and Stillbirth”.Obstetrics and Gynecology 3 (2020): 644-652.

Citation

Citation: Paul H Hartel., et al. “Umbilical Cord Index and Placental Intervillous Thrombi: Implications for Clinical Management".Acta Scientific Women's Health 5.12 (2023): 03-05.

Copyright

Copyright: © 2023 Paul H Hartel., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US