Ramiro Cabrera¹*, Andrea Carrillo², Felipe Esparza³ and Sylvia Salmun³

¹Director del Departamento en Cirugía Pélvica, Doyenne High Quality and Multidisciplinary Treatment Center for Endometriosis, Mexico
²Departamento en Cirugía Pélvica, Doyenne High Quality and Multidisciplinary Treatment Center for Endometriosis, Mexico
³Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud Universidad Anáhuac México Norte, Mexico

*Corresponding Author:Ramiro Cabrera, Director del Departamento en Cirugía Pélvica, Doyenne High Quality and Multidisciplinary Treatment Center for Endometriosis, Mexico.

Received: August 20, 2023; Published: October 19, 2023

Abstract

Endometriosis is a chronic and inflammatory disease that affects women of any age. It is a benign inflammatory condition in which endometrial-like tissue is located outside the endometrial cavity. In women of reproductive age, the global incidence of endometriosis is approximately 10-15%, but it can escalate to as high as 35-50% in women experiencing infertility. Presentation varies widely, ranging from asymptomatic individuals to those experiencing varying levels of dysmenorrhea, chronic pelvic pain, dysuria, dyschezia, dyspareunia, asthenia, headaches, and infertility. Diagnostic supporting tools such as imaging studies, primarily ultrasound and magnetic resonance imaging with an endometriosis mapping protocol, demonstrate exceptional sensitivity and specificity when utilized by expert professionals. However, there is a significant delay in diagnosis, typically ranging from 7 to 12 years. Multiple factors contribute to this delay, including challenges in making differential diagnoses, insufficient expert healthcare professionals, lack of clinical judgment and social awareness regarding the disease, and difficulties accessing necessary resources. Today, there is a solid effort to minimize this delay by training healthcare professionals and promoting social awareness among patients, as well as developing easily accessible tools to identify high-risk patients enabling the prompt initiation of appropriate study protocols. Implementing symptom-based questionnaires has been a subject of ongoing debate, primarily due to the controversial results obtained from previous studies. This review aims to contribute to the scientific literature by providing robust evidence to validate their utilization as a first-line tool.

Keywords: Endometriosis; Dysmenorrhea; Pelvic Pain; Dyspareunia; Health Questionnaires and Diagnostic Tools

References

1. Ballard KD., et al. “Can symptomatology help in the diagnosis of endometriosis? Findings from a national case-control study--Part 1”. BJOG 11 (2008): 1382-1391.
2. Koninckx PR., et al. “Pathogenesis Based Diagnosis and Treatment of Endometriosis”. Frontiers in Endocrinology (Lausanne) 12 (2021): 745548.
3. Smolarz B., et al. “Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature)”. International Journal of Molecular Sciences 19 (2021): 10554.
4. Rolla E. “Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment”. F1000Research 8 (2021): F1000 Faculty Rev-529.
5. Staal AH., et al. “Diagnostic Delay of Endometriosis in the Netherlands”. Gynecologic and Obstetric Investigation 81 (2016): 321-324.
6. Wyrwich KW., et al. “Development and Validation of the Endometriosis Daily Pain Impact Diary Items to Assess Dysmenorrhea and Non- menstrual Pelvic Pain”. Reproductive sciences (thousand oaks, calif) 25 (2018): 1567-1570.
7. Surrey E., et al. “Patient-completed or symptom- based screening tools for endometriosis: a scoping review”. Archives of Gynecology and Obstetrics 296 (2017): 153-165.
8. Gruber TM., et al. “Pathogenesis of Endometriosis: The Origin of Pain and Subfertility”. Cells 6 (2021): 1381.
9. Kapoor R., et al. “Pathogenesis of Endometriosis: New Insights into Prospective Therapies”. International Journal of Molecular Sciences 21 (2021): 11700.
10. Vercellini P., et al. “Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients”. Human Reproduction 22 (2007): 266-271.
11. Nnoaham KE., et al. “Developing symptom- based predictive models of endometriosis as a clinical screening tool: results from a multicenter study”. Fertility and Sterility 98 (2012): 692-701.e695.
12. Chapron C., et al. “Rethinking mechanisms, diagnosis and management of endometriosis”. Nature Reviews Endocrinology 11 (2019): 666-682.
13. Jones G., et al. “Measuring quality of life in women with endometriosis: tests of data quality, score reliability, response rate and scaling assumptions of the Endometriosis Health Profile Questionnaire”. Human Reproduction 21 (2006): 2686-2693.
14. Van Nooten FE., et al. “Development and content validation of a patient-reported endometriosis pain daily diary’. Health Quality Life Outcomes 16 (2018): 3.
15. Johnson NP., et al. “World Endometriosis Society consensus on the classification of endometriosis”. Human Reproduction 32 (2017): 315-324.
16. Hsu AL., et al. “Invasive and noninvasive methods for the diagnosis of endometriosis”. Clinical Obstetrics and Gynecology 53 (2010): 413-419.
17. Taylor HS., et al. “Endometriosis is a chronic systemic disease: clinical challenges and novel innovations”. Lancet 10276 (2021): 839-852.
18. Sachedina A and Todd N. “Dysmenorrhea, Endometriosis and Chronic Pelvic Pain in Adolescents”. Journal of Clinical Research in Pediatric Endocrinology 12 (2020): 7-17.
19. Deal LS., et al. “The development and validation of the daily electronic Endometriosis Pain and Bleeding Diary”. Health Qual Life Outcomes 8 (2010): 64.
20. Dunselman GA., et al. “European Society of Human Reproduction and Embryology. ESHRE guideline: management of women with endometriosis”. Human Reproduction3 (2014): 400-412.
21. ACOG Committee Opinion No. 760: Dysmenorrhea and Endometriosis in the Adolescent. Obstetrics and Gynecology6 (2018): e249-e258.
22. Hans Evers JL. “Is adolescent endometriosis a progressive disease that needs to be diagnosed and treated?”. Human Reproduction8 (2013): 2023.
23. Gutman G., et al. “Dysmenorrhea in adolescents”. Current Problems in Pediatric and Adolescent Health Care5 (2022): 101186.
24. Clemenza S., et al. “Is primary dysmenorrhea a precursor of future endometriosis development?” Gynecology and Endocrinology4 (2021): 287-293.
25. Gater A., et al. “Development and content validation of two new patient-reported outcome measures for endometriosis: the Endometriosis Symptom Diary (ESD) and Endometriosis Impact Scale (EIS)”. The Journal of Patient-Reported Outcomes1 (2020): 13.
26. Ghai V., et al. “Diagnostic delay for superficial and deep endometriosis in the United Kingdom”. Journal of Obstetrics and Gynaecology 1 (2020): 83-89.
27. Omboni S and Caserini M. “Effectiveness of pharmacist's intervention in the management of cardiovascular diseases”. Open Heart1 (2018): e000687.
28. Firth J., et al. “The efficacy of smartphone-based mental health interventions for depressive symptoms: a meta-analysis of randomized controlled trials”. World Psychiatry3 (2017): 287-298.
29. McLean G., et al. “Digital interventions to promote self- management in adults with hypertension systematic review and meta-analysis”. Journal of Hypertens4 (2016): 600-612.

Citation

Citation: Ramiro Cabrera., et al. “Association of Dysmenorrhea with Endometriosis: a Literature Review".Acta Scientific Women's Health 5.11 (2023): 24-29.

Copyright

Copyright: © 2023 Ramiro Cabrera., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.