The Causation of Preeclampsia: An Unresolved Question
Jaime Salvador-Moysén*, Yolanda Martínez-López and Ana Cristina Castañeda-Márquez
Academic Group of Public Health and Epidemiology, Institute of Scientific Research, Universidad Juárez del Estado de Durango, México
*Corresponding Author: Jaime Salvador-Moysén, Academic Group of Public Health and Epidemiology, Institute of Scientific Research, Universidad Juárez del Estado de Durango, México.
Received:
July 07, 2023; Published: August 04, 2023
Abstract
In this article a brief review of the most important scientific advances related to preeclampsia is made from the following perspectives; clinical, epidemiological and pathophysiological. The topics addressed are located within a broad framework, it stands out to the importance that a wide diversity of geographical, socioeconomic, clinical, nutritional and psychosocial conditions have had for the expression of this health problem. The enormous advance in knowledge that has been generated in the identification of the pathophysiological processes of the disease is underlined, as well as in the existence of screening procedures with high predictive values. The paper discusses the validity of the reductionist strategies that have prevailed over time, with the purpose of identifying the causal framework of preeclampsia, although the value they have had for the identification of specific clinical, pathophysiological and molecular processes is recognized; its usefulness for addressing the causality of the disease is questioned. This critique of reductionist approaches is supported by recent scientific information. Finally, it is suggested that an Eco- epidemiological approach represents a better strategy for the identification of the causal framework of preeclampsia.
Keywords: Preeclampsia; Causality; Investigation; Eco-epidemiology; Risk Factors; Reductionism
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