Danielle Walsh1, Sandra Pawlus1, Patricia Commins1 and Paul H Hartel2-4*
1Department of Forensic Investigation and Analysis, Atlantic Technological University, Ireland
2Sligo University Hospital, Department of Pathology, Ireland
3National University of Ireland, Galway School of Medicine, Department of Pathology, Ireland
4West Virginia University School of Medicine, Department of Medicine, USA
*Corresponding Author: Paul H Hartel, Sligo University Hospital, Department of Pathology, Ireland.
Received: September 05, 2022; Published: September 13, 2022
Single artery umbilical cords have conventionally been studied in relation to clinical abnormalities such as intrauterine growth restriction (IUGR) and chromosomal abnormalities. Literature on the histopathologic correlates of single artery umbilical cords is lacking. We evaluated umbilical cord, foetal membrane and placental histopathologic findings in 26 placentas with single artery umbilical cords to characterise any differences compared to normal three-vessel umbilical cord control cases. We found a greater prevalence of funisitis and acute chorioamnionitis, and greater prevalence of maternal vascular malperfusion. Umbilical cord and/or foetal membrane inflammation and placental histology of maternal vascular malperfusion often correlate with clinical infection and hypertension, respectively. Early in-utero detection of single artery umbilical cord may therefore help identify risk of potential infection and maternal/foetal hypertension and help prevent adverse clinical sequelae.
Keywords: Two-Vessel Umbilical Cord; Single Umbilical Artery; Funisitis; Chorioamnionitis; Maternal Vascular Malperfusion
Citation: Paul H Hartel., et al. “Histologic Correlates of Single Artery Umbilical Cords with Clinical Implications". Acta Scientific Women's Health 4.10 (2022): 13-16.
Copyright: © 2022 Paul H Hartel., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.