Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Case Report
Neuroendocrine Primary Carcinoma of the Small-cell Breast of High Grade - Case Report and Literature Review

Brandenburg Thais1*, Maciel Marcio2, Acosta Leandro3, Bueno Alexandre4 and Gardin Caio5

1Department of Intern Medicine, Assis Gurgacz University Center, Brazil
2Clinical Oncology Department, COOP - Oeste do Paraná Oncology Center, Federal University of Health Sciences of Porto Alegre, Brazil
3Oncology Surgery Department, COOP - Oeste do Paraná Oncology Center, Federal University of Mato Grosso do Sul, Brazil
4Department of Clinical Pathology and Laboratory Medicine, Medical Sciences of Santa Casa de São Paulo, Brazil
5Anesthesiology Department, Norospar, Vassouras University of Rio de Janeiro, Brazil

*Corresponding Author: Brandenburg Thais, Doctor Working in the Areas of Emergency, General Practice and Intensive Care Unit, Department of Intern Medicine, Assis Gurgacz University Center, Brazil.

Received: March 28, 2022; Published: May 2, 2022


The primary neuroendocrine carcinoma of the small-cell breast of high grade is an extremely rare and aggressive tumor, accounting for less than 1% of cases of malignant tumors of the organ. There are only about 35 cases reported in the literature. The present study aims to report an unusual case of this neoplasm with a description of the clinical characteristics, histopathological findings, immunohistochemical findings and evolution of the disease, as well as a systematic review of the literature. the case of undifferentiated neuroendocrine carcinoma of small breast cells in a female patient of 56 years old was reported, presenting a perceptible QSL nodule of the left breast. The lesion was biopsied, and the pathology confirmed by immunohistochemistry. Patient was submitted to surgical treatment followed by chemotherapy and adjuvant radiotherapy.

Keywords: Neuroendocrine Tumor; Breast Cancer; Small Cell Carcinoma; Extrapulmonary Carcinoma; Immunohistochemistry


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Citation: Brandenburg Thais., et al. “Neuroendocrine Primary Carcinoma of the Small-cell Breast of High Grade - Case Report and Literature Review". Acta Scientific Women's Health 4.6 (2022): 06-10.


Copyright: © 2022Brandenburg Thais., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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