Case Report

Neuroendocrine Primary Carcinoma of the Small-cell Breast of High Grade - Case Report and Literature Review

Brandenburg Thais¹*, Maciel Marcio², Acosta Leandro³, Bueno Alexandre⁴ and Gardin Caio⁵

¹Department of Intern Medicine, Assis Gurgacz University Center, Brazil
²Clinical Oncology Department, COOP - Oeste do Paraná Oncology Center, Federal University of Health Sciences of Porto Alegre, Brazil
³Oncology Surgery Department, COOP - Oeste do Paraná Oncology Center, Federal University of Mato Grosso do Sul, Brazil
⁴Department of Clinical Pathology and Laboratory Medicine, Medical Sciences of Santa Casa de São Paulo, Brazil
⁵Anesthesiology Department, Norospar, Vassouras University of Rio de Janeiro, Brazil

*Corresponding Author: Brandenburg Thais, Doctor Working in the Areas of Emergency, General Practice and Intensive Care Unit, Department of Intern Medicine, Assis Gurgacz University Center, Brazil.

Received: March 28, 2022; Published: May 2, 2022

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Abstract

The primary neuroendocrine carcinoma of the small-cell breast of high grade is an extremely rare and aggressive tumor, accounting for less than 1% of cases of malignant tumors of the organ. There are only about 35 cases reported in the literature. The present study aims to report an unusual case of this neoplasm with a description of the clinical characteristics, histopathological findings, immunohistochemical findings and evolution of the disease, as well as a systematic review of the literature. the case of undifferentiated neuroendocrine carcinoma of small breast cells in a female patient of 56 years old was reported, presenting a perceptible QSL nodule of the left breast. The lesion was biopsied, and the pathology confirmed by immunohistochemistry. Patient was submitted to surgical treatment followed by chemotherapy and adjuvant radiotherapy.

Keywords: Neuroendocrine Tumor; Breast Cancer; Small Cell Carcinoma; Extrapulmonary Carcinoma; Immunohistochemistry

References

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Citation

Citation: Brandenburg Thais., et al. “Neuroendocrine Primary Carcinoma of the Small-cell Breast of High Grade - Case Report and Literature Review". Acta Scientific Women's Health 4.6 (2022): 06-10.

Copyright

Copyright: © 2022Brandenburg Thais., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.