Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Editorial Volume 4 Issue 2

Epithelial to Mesenchymal Transition (EMT): A New Target for Anticancer Drugs

Maithili A Athavale*

1MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor, Malaysia
2Bachelor of Science Biology at Sunway University, Bandar Sunway, Subang Jaya, Selangor, Malaysia

*Corresponding Author: Maithili A Athavale, Assistant General Manager (R&D), Cancer Biology Lab, Sathgen Biotech - A Unit of Godavari Biorefineries Ltd., India.

Received: December 24, 2021; Published: January 01, 2022

The process by which epithelial cells are transformed into mesenchymal cells is called EMT. The epithelial tissue covers the internal and external body surface of an organism. Epithelial cells are polarized and they form the extensive cell-cell adhesions, including the tight junctions, with each other. These cells form the protective barrier for underlying tissues and organs. However, mesenchymal cells are not very well organized in three dimensional extracellular matrixes.

During the process of EMT, the epithelial cells lose their polarity as well as cell-cell adhesions and gain the ability to migrate, proliferate, differentiate and develop into specific tissues and organs.


Citation: Maithili A Athavale. “Epithelial to Mesenchymal Transition (EMT): A New Target for Anticancer Drugs". Acta Scientific Women's Health 4.2 (2022): 01.


Copyright: © 2022 Maithili A Athavale. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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