Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 3 Issue 8

Echocardiographic and Electrocardiographic Manifestations of Newly Diagnosed Adult Patients Suffering with Overt Hyperthyroidism

Rashmi Aggarwal1*, Hemant Aggarwal2, Pradeep Chugh1 and Vipin VS1

1Department of Thyroid and Endocrine Research, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India
2Deputy Medical Superintendent, B K Hospital, Faridabad, Haryana, India

*Corresponding Author: Rashmi Aggarwal, Department of Thyroid and Endocrine Research, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India.

Received: July 16, 2021; Published: July 26, 2021

Abstract

Background: Thyroid hormones directly affect the heart and cardiovascular system. Cardiovascular symptoms like hypertension, palpitations, dyspnoea, chest pain, pedal edema and exercise intolerance are common presenting symptoms of hyperthyroidism. These symptoms usually revert back to normal when a euthyroid state is restored and maintained with help of antithyroid drugs initially and a definitive treatment later. Hyperthyroid patients can be easily evaluated using two non invasive modalities namely electrocardiography and echocardiography. This study aims at understanding the various electrocardiographic and echocardiographic manifestations of newly diagnosed patients with overt hyperthyroidism.

Aim: To evaluate electrocardiographic and echocardiographic manifestations of newly diagnosed adult patients suffering with overt hyperthyroidism.

Methods: 77 patients with overt hyperthyroidism who visited the thyroid clinic of Institute of nuclear medicine and allied science (INMAS), Timarpur, Delhi were enrolled for the present study. All the patients were asked about the symptoms including cardiac symptoms with the help of a structured questionnaire. Detailed clinical, biochemical evaluation and nuclear imaging was done for all the patients and it included estimation of freeT3, free T4, TSH, Technetium 99 scan and Radio-active iodine uptake. Cardiovascular evaluation included a 12 lead resting electrocardiogram (ECG) and a two dimensional transthoracic echocardiogram.

Conclusion: Symptoms pertaining to cardiovascular system are the common presenting feature in patients with hyperthyroidism. Apart from clinical examination of the cardiovascular system electrocardiography and echocardiography are two non-invasive modalities that can evaluate the cardiac abnormalities in such patients.

Keywords: Hyperthyroidism; Hemodynamic Changes; Arrythmias

References

  1. Parmar MS. “Thyrotoxic atrial fibrillation”. Medscape General Medicine1 (2005): 74.
  2. Osman F. “Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy: a matched case-control study”. Journal of the American College of Cardiology 1 (2007): 71-81.
  3. “Thyrotoxicosis”. Annals of Saudi Medicine 20.5-6 (2000): 484-487.
  4. Marcisz C., et al. “The systolic function of the left ventricle of heart in patients with hyperthyroidism during therapy”. Polish Archives of Internal Medicine 2 (2001): 131-138.
  5. Kiss E., et al. “Thyroid hormone induced alternation in phosholamban protein expression :regulatory effects in sarcoplasmic reticulum Ca2+ transport and myocardial relaxation”. Circulation Research 75 (1994): 245-251.
  6. Mintz G., et al. “Enhanced left ventricular diastolic function in hyperthyroidism: non invasive assessment and response to treatment”. Journal of Clinical Endocrinology and Metabolism 73 (1991): 146-150.
  7. Yue WS., et al. “Hyperthyroidism-induced left ventricular diastolic dysfunction: implication in hyperthyroidism-related heart failure”. Clinical Endocrinology (Oxf)5 (2011): 636-643.

Citation

Citation: Rashmi Aggarwal., et al. “Echocardiographic and Electrocardiographic Manifestations of Newly Diagnosed Adult Patients Suffering with Overt Hyperthyroidism". Acta Scientific Women's Health 3.8 (2021): 53-56.

Copyright

Copyright: © 2021 Rashmi Aggarwal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US