Anita Kant¹*, Usha Priyambada Gupta², Amrita Razdan Kaul³ and Shephali⁴

¹Chairman, Department of Obstetrics and Gynaecology, Asian institute of Medical Sciences, Faridabad, Haryana, India
²Senior Consultant, Department of Obstetrics and Gynaecology, Asian institute of Medical Sciences, Faridabad, Haryana, India
³Consultant, Department of Obstetrics and Gynaecology, Asian Institute of Medical Sciences, Faridabad, Haryana, India
⁴DNB Resident, Final Year, Department of Obstetrics and Gynaecology, Asian institute of Medical Sciences, Faridabad, Haryana, India

*Corresponding Author: Anita Kant, Chairman, Department of Obstetrics and Gynaecology, Asian institute of Medical Sciences, Faridabad, Haryana, India.

Received: June 17, 2021; Published: July 09, 2021

Abstract

Objective: To study the safety and efficacy of Tranexamic acid (TXA) in reducing blood loss during and after the caesarean section.

Methodology: This is a randomized, case controlled, prospective open label trial conducted on ninety term pregnant females undergoing caesarean in our hospital for evaluating the blood loss with or without the use of TXA. Patients were randomly assigned to either cases (Receiving injection TXA) or controls (Not receiving TXA).

Results: Mean of total blood loss among cases was 267.27 ± 115.77 ml, while it was 428.13 ± 98.24 ml in controls (p value < 0.001). Its use was not associated with any side effect or complications like Thrombosis. Overall, the study supports the evidence of beneficial effects of TXA in significantly reducing blood loss during and after CS and hence reducing the need for blood transfusion.

Conclusion: TXA is effective in reducing blood loss during and after caesarean section.

Keywords: Bleeding; Caesarean Section; Postpartum; Tranexamic Acid

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Citation

Citation: Anita Kant., et al. “Effects of Intravenous Administration of Tranexamic Acid in Reducing Blood Loss during and After Caesarean Section”. Acta Scientific Women's Health 3.8 (2021): 11-15.

Copyright

Copyright: © 2021 Anita Kant.,et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.