Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Case Study Volume 3 Issue 7

Hemoglobin Electrophoresis - A Stitch in Time Saved Beta thalassemia Mother and Newborn

Preeta Kurvattigoudar1* and Kishanrao Suresh2

1Karnataka State Rural Development and Panchya Raj University (KSRDPRU), Gadag, Karnataka, India
2Visiting Professor-MPH, KSRDPRU, Karnataka State Rural Development and Panchya Raj University (KSRDPRU), Gadag, Karnataka, India

*Corresponding Author: Preeta Kurvattigoudar, Karnataka State Rural Development and Panchya Raj University (KSRDPRU), Gadag, Karnataka, India.

Received: June 01, 2021; Published: June 29, 2021

Abstract

Hemoglobinopathies are inherited disorders of red blood cells,an important cause of morbidity and mortality, as they impose a heavy burden on families in the absence of a antional program. People with Beta thalassemia minor exibit mild anemia needing no medical treatment but if the client be a lady may fall short of Hb% during pregnancies. We report one such case of Beta-thalassemia. An young female of 30 yrs, married for 4 years a housewife reported happily with amenorrhea for 2.5 months and a positive pregnancy test using a rapid test kit at home for routine check-up, follow-up, expecting normal outcome. She revealed normal menstrual history but the exact LMP was not known. Her past history indicated delayed developmental milestones following her mother’s death an obstructed delivery by outlet forceps.

Physical examination revealed a uterus of 16 weeks size, urinary pregnancy test reconfirmed the pregnancy and all other findings were normal. Gestational diabetes was ruled out by a GTT. Investigation reports showed that Hb was 8.2 gm% with MCV count 69fL, WBC count was 7400 cells/ cumm and Platelet count was 301000 cells/cumm, Red blood cells count was 3.7 million. HIV and HbsAg were also negative and the patient blood group was “O” positive. Cardiotocography showed FHS (Fetal Heart Sound) ranging from 150 - 160 beets/min. An anomaly scan reported that a single live intrauterine fetus of gestational age 17wks 2 days +- 8 days with no obvious anomalies. And EDD (Expected Date of Delivery) was given on 28 September 2020. T. Iron and a multivitamin -Bd for 30 days. And T. calcium carbonate 600 mg + T. Vitamin D3 400 Iu - od for 30 days was given. Same follow-up was repeated, but Hb% did not improve after 3 more months. An USG was normal. Hemoglobin electrophoresis confirmed that she had Beta thalassemia trait in the 7th month of the pregnancy. She was given Inj. OROFER FCM 500 mg IV that improved the Hb% level to 10 gm%. As a result she underwent a full term lower segment Cessarian Section (LSCS) on 21st September 2020, No complications durng the entire process of LSCS. Both mother and baby with birth weight of about 2900 gms were healthy. No further peurperal complications were observed. Now the baby turned to 8th month with no such issues and Hb% of the mother mentained same as 10 gm% and the growth and development of the newborn are normal.

Keywords: Hemoglobin Electrophoresis; Hereditary; Diabetes Mellitus

References

  1. pdf
  2. Hemoglobin electrophoresis, Blood and Bone Marrow Pathology (Second Edition) (2011).
  3. Nitu Nigam., et al. “A demographic prevalence of β Thalassemia carrier and other hemoglobinopathies in adolescent of Tharu population”. Journal of Family Medicien and Primary Care8 (2020): 4305-4310.
  4. V Gomathi., et al. “Parenteral Iron Therapy for Treatment of Moderate - Severe anemia in Pregnancy”. 3.10 (2016).
  5. Kanjaksha Ghosh., et al. “Guidelines for screening, diagnosis and management of hemoglobinopathies”. Indian Journal of Human Genetics 2 (2014): 101-119.
  6. Ramesh Agarwal., et al. “Thalassemia: An overview”. Journal of the Scientic Society1 (2014): 3-6.
  7. Dr Sudeshna Ray. “Thalassemia in Pregnancy- A High Risk” (2011).
  8. SitaramBharati Team. “Thalassemia in Pregnancy-Tests, Types and Tips”.
  9. P Kulkarni. “The Prevalence of the Beta Thalassemia Trait among the Pregnant Women who attended the ANC Clinic in a PHC”. Journal of Clinical and Diagnostic Research 7 (2013): 1414-1417.
  10. Asha Baxi., et al. “Carrier Screening for β Thalassemia in Pregnant Indian Women”. Indian Journal of Hematology and Blood Transfusion 2 (2013): 71-74.

Citation

Citation: Preeta Kurvattigoudar and Kishanrao Suresh. “Hemoglobin Electrophoresis - A Stitch in Time Saved Beta thalassemia Mother and Newborn". Acta Scientific Women's Health 3.7 (2021): 34-38.

Copyright

Copyright: © 2021 Preeta Kurvattigoudar and Kishanrao Suresh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2022.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US