Biodegradable Polymeric Nanoparticles for Photodynamic Laser Cancer Therapy
Mohammadreza Saboktakin*
Professor, Nanomedicine Department, NanoBMat Company GmbH, Düsseldorf, Germany
*Corresponding Author: Mohammadreza Saboktakin, Professor, Nanomedicine Department, NanoBMat Company GmbH, Düsseldorf, Germany.
Received:
April 08, 2021; Published: May 11, 2021
Abstract
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Abstract
Photodynamic cancer therapy is well known and recognized in many countries best therapy for cancer therapy. However, previous findings on PDT are limited to Tumors on the body surface, since the available photosensitizers largely from Porphyrin exist and can only be stimulated with red laser light. The penetration depth of the red laser with effective stimulation of the photosensitizer is about 1 - 2 cm and also limited to a tumor size of about 1 cm. The penetration into the liver or through bone is almost impossible, so that there is no possibility. To successfully treat liver metastases or brain tumors. Infrared laser beams penetrate a lot deeper into the body and can even penetrate liver and bone. A perfect one Photosensitizer should therefore have an absorption spectrum in the infrared range, in the market however, nothing is available. The new polymeric systems have reviewed in this review.
Keywords: Liver; Bone; Cancer Therapy; Nanoparticles
References
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