Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 3 Issue 1

Pre-implementation Genetics for Aneuploidy Interpretation in PGT-A Goals Indications and Improve Infertility Outcomes, ART, and How to Perform PGT-A

Aya Al-ibraheemi1* Mustafa Zakaria2*, Noureddine Louanjli3, Mohamed Zarqaoui4, Mohamed Ennaji5, Senhaji R Wassym6, Ritu S Santwani7, Nisrine En-naciri8, Hafida Tarik8 and Romaissa Boutiche9

1Embryologist, Graduated from University of Nottingham, United Kingdom
2Reproductive Biology, and Assisted Reproductive Technology, Consultant at IRIFIV Fertility Center, Administrative Deputy and Writer for the ART IRIFIV Scientific Research Group (AISRG) Casablanca, Morocco
3Head of LABOMAC Laboratory of Clinical Analysis and Assisted Reproductive Technology IRIFIV Fertility Center, AFC Fertility Center - Executive Vice President of the ART IRIFIV Scientific Research Group (AISRG) Casablanca, Morocco
4Endoscopic Surgery Obstetrics and Gynecology FR, Coordinator of IRIFIV Fertility Center, Head of the ART IRIFIV Scientific Research Group (AISRG) Casablanca, Morocco
5Senior Clinical Embryologist at IRIFIV Fertility Center, Member of the Scientific Research Group and Researcher in the Scientific Research Group, Casablanca, Morocco
6Gynecologist and Obstetrician, Endoscopic Surgeon and Fertility Expert, A Research in Art Irifiv Scientific Research Group Associated Practitioner at IRIFIV Fertility Center – Casablanca, Morocco
7Gynaecologist and Obstetrician, ART-Singapore, Honorary Professor, India
8Senior Clinical Embryologist, Laboratory IVF Agadir, Souss-Massa, Member of the Scientific Research Group and Researcher in the Scientific Research Group, Agadir, Morocco
9Senior Clinical Embryologist, Laboratory IVF Algeria, Rotaby Fertility Center Algeria - Algiers, Member of the Scientific Research Group and Researcher in the Scientific Research Group, Algeria

*Corresponding Author: Mustafa Zakaria, Consultant at IRIFIV Fertility Center, Administrative Deputy and Writer for the ART IRIFIV Scientific Research Group (AISRG), Casablanca, Morocco.

Received: November 21, 2020; Published: December 15, 2020

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Abstract

  Preimplantation genetic testing for aneuploidy PGT-A has been widely applied today in assisted reproductive technology treatments centers over the world to select the health embryos for transfer with euploid cells and to enhance clinical outcomes such as embryo implantation, clinical pregnancy, and live birth rates. The PGT-A can be performed in during an IVF cycle, after fertilization where a biopsy can be taken from the blastocysts to be genetically tested. PGT-A indication can be to decrease recurrent miscarriage, increase the pregnancy rate in advance maternal age, and increase single embryo transfer. This review also demonstrates new PGT-A method which is called non-invasive PGT-A, to prevent the embryo development distracting and removing extra cells from the embryo, through analyzing leaked DNA.

Keywords: Infertility and ART; PGT and PGT-A; How to Perform PGT-A; Blastocytes Biopsy Steps; PGT-A Goals/Indication; PGT-A Interpretation; Non-invasive PGT-A

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Citation

Citation: Mustafa Zakaria., et al. “Pre-implementation Genetics for Aneuploidy Interpretation in PGT-A Goals Indications and Improve Infertility Outcomes, ART, and How to Perform PGT-A". Acta Scientific Women's Health 3.1 (2021): 08-14.




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