Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 2 Issue 10

A Prognostic Tool to Predict the Development of Postpartum Endometritis and Haematometra

Bulavenko O1, Ostapiuk Lesia1,2*, Rud V1 and Rud O3

1Department of Obstetrics and Gynaecology, Vinnytsia National Medical University of the Ministry of Health of Ukraine, Ukraine
2Lviv Regional Public Health Center, Lviv, Ukraine
3Country Clinical Operations, Roche Products Limited, Welwyn Garden City, United Kingdom

*Corresponding Author: Ostapiuk Lesia, Vinnytsia National Medical University of the Ministry of Health of Ukraine, Lviv Regional Public Health Center, Lviv, Ukraine.

Received: September 03, 2020; Published: September 28, 2020



Introduction: Obstetric sepsis remains one of the top 5 causes of maternal death in Ukraine, according to the data collected between 2009 - 2015. Postpartum purulent-inflammatory diseases are the reason of sepsis occurrence. Currently, there is a lack of methods of early diagnostics of postpartum endometritis (PPE).

Objectives: The main aim is to evaluate the risks of postpartum endometritis (PPE) among postpartum women and development of means of its early diagnosis using fluorescent spectroscopy. In addition, the reliability of such approach is tested via creation of a prognostic model.

Methods: Fluorescent spectroscopy was used, along with the standard diagnostic tools in order to diagnose 170 postpartum patients of the participants cohort and 40 postpartum patients of the control group with uncomplicated course of postpartum period.

Results: By statistical analysis using logistic regression, the data was evaluated according to more than 40 indicators and as a result, a prognostic model was derived. This prognostic model enables to assess the probability of development of postpartum endometritis among postpartum patients. ROC-analysis was implied in order to evaluate the quality of the proposed model.

Conclusion: Proposed multi-structured model for prognosis of the development of PPE among postpartum women, which enables determination of the patient groups susceptible to develop PPE. The major risk factors in the finalised multi-structured model of the development of PPE are: extragenital pathology, risk of miscarriage, TORCH-infections, colpitis, labour duration > 12 hrs, abnormal labour, lambda (λ) max, fluorescence intensity ≤ 0,845, a number of bed days and the presence of foetal distress.

It was confirmed, that the results obtained by using fluorescent spectroscopy have the highest significance among the prognostic tools used in the investigation. Therefore, application of this prognostic tool in clinical practice is a highly feasible way to improve diagnosis and prognosis of the development of postpartum endometritis.

Keywords: Postpartum Endometritis; Fluorescent Spectroscopy; Prognostic Model; Haematometra; ROC-Analysis



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Citation: Ostapiuk Lesia., et al. “A Prognostic Tool to Predict the Development of Postpartum Endometritis and Haematometra". Acta Scientific Women's Health 2.10 (2020): 18-23.


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