Acta Scientific Women's Health (ASWH)(ISSN: 2582-3205)

Research Article Volume 2 Issue 2

Inhibition Aggregation of Platelets with using Nanoparticles of Magnet-Controlled Sorbent (MCS-B) In Vitro Experiment

Andrey N Belousov*

Laboratory of Applied Nanotechnology of Belousov, Department of Anesthesio logy, Intensive Care, Transfusiology and Hematology, Kharkov Medical Academy of Postgraduate Education, Ukraine

*Corresponding Author: Andrey N Belousov, Laboratory of Applied Nanotechnology of Belousov, Department of Anesthesiology, Intensive Care, Transfusiology and Hematology, Kharkov Medical Academy of Postgraduate Education, Ukraine.

Received: December 16, 2019; Published: January 03, 2020

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Abstract

  This scientific article is devoted to the study of the effect of magnetite nanoparticles (MCS-B brand) on the functional platelets activity of human. 0.9% NaCl was used as a control. The results of the study showed that the use of NaCl saline solution shifts the colloidal suspension equilibrium of platelets towards a significant (P<0.001) increase in the rate and index of their aggregation. For the first time, the effect of 0.9% NaCl on function of platelets makes us reconsider the concept of safety of infusion solutions in patients with initial signs of platelet disorders hemostasis. On the contrary, the use of MCS-B nanoparticles significantly revealed (P<0.05) an increase in the stability of colloidal suspension of platelets. This is an important pathogenetic factor which affects the occurrence of correction of hemostasis in conditions of blood clotting disorders.

Keywords: Platelets; Functional; MCS-B Nanoparticles; Saline Solution; Aggregation Rate; Aggregation Index

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Citation

Citation: Andrey N Belousov. “Inhibition Aggregation of Platelets with using Nanoparticles of Magnet-Controlled Sorbent (MCS-B) In Vitro Experiment”. Acta Scientific Women's Health 2.2 (2020): 08-14.




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