Rishabh Kumar*

Ophthalmologist, India

*Corresponding Author: Rishabh Kumar, Ophthalmologist, India

Received: March 11, 2025; Published: March 31, 2025

Abstract

The two distinct types of epithelial cells are present in conjunctiva and cornea. Although getting continuous anatomically, the two distinct cell population get comprise by their epithelia. The limbus locate the corneal stem cells. The stembess of stem cells is important in maintaining the microenvironment of the limbus and conjunctival epithelial cells act as a barrier preventing to migrate onto the surface of cornea. The limbal damage results in limbal stem cells deficiency to varying degrees, including conjunctiva location of cornea as it’s characteristic clinical features. Two approaches get comprise as regenerative management of corneal conjunctival satin utilising stem cells, one as limbal onto and the other as allograft by the use of existing stem cells and regeneration and inducting of ocular tissues from embryonic stem cells. Herein we review stem cells and limbal stem cells along with different types of epithelial cells in the cornea, different stages of markers of corneal epithelial cells as well as current approach towards corneal epithelial generation.

Keywords: Conjunctiva; Cornea; Epithelial Cells

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Citation

Citation: Rishabh Kumar. “Limbal Stem Cells: A Review".Acta Scientific Ophthalmology 8.4 (2025): 26-33.

Copyright

Copyright: © 2025 Rishabh Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.