Alvina D Musina*

Senior Scientist, Moscow, Russia

*Corresponding Author: Alvina D Musina, Senior Scientist, Moscow, Russia.

Received: September 26, 2023; Published: December 21, 2023

Abstract

As the quality and complexity of surgical interventions improve, for example, in the anterior segment of the eyeball, it becomes necessary to improve the quality of not only medical instruments, but also the use of various methods for successful rehabilitation in the postoperative period. Upon completion of surgery on the eyeball, more precisely, on the anterior segment of the eyeball, Therapeutic Contact Lenses (TCL) are widely used to accelerate and correct the healing of the Cornea. Soft contact lenses (SCLs) are used instead of specially made therapeutic contact lenses (TCLs). Because there is no TCL production. Ophthalmologists are well aware of eye diseases in patients using SCL, sometimes very severe and dangerous, complications that occur more often due to violations of the mode and hygiene of wearing SCL and due to allergic reactions to the polymer material of the SCL. Many items widely used in medicine and biology are made using inexpensive polymer products that must meet specific clinical and cost requirements. The main requirements for polymer products are the need to ensure the aseptic properties of the polymer product, biocompatibility between the physiological environment and the polymer surface of the product, which can be achieved by treating the polymer surface by applying carbon-containing films (CCF), such as diamond-like, carbine-containing, carbine-containing, carbon nanotubes. Nano structuring of the surface of polymeric materials (Surface Nanomodification-SNM) is carried out to achieve biocompatibility, aseptic and thus certain multifunctionality properties of the polymeric materials used. The aim of our work was to create the first truly therapeutic contact lenses for use in the period of postoperative rehabilitation of the eye after operations on the anterior segment of the eyeball. So far, conventional corrective soft contact lenses (SCLs) have been used as TCLs (Therapeutic Contact Lenses).
For the manufacturing of TCL, the same polymeric materials are used: polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE) and polyvinylidene fluoride (PVDF) on the same line for the manufacturing of SCL; followed by treating of their surface by applying carbon-containing films deposition, additionally to the process of SCL obtaining. Modification is carried out by deposition of nanocomposites from directed ion-plasma flows of vapors of gas mixtures or by magnetron deposition.
The shape of the TCL is also modified in such a way that on the inner surface of the empirically aspherical shape of the manufactured TCL, which has a uniform smooth surface, there are no dividing zones, such as: optical, sliding, which makes the surface smooth, uniform, without surface irregularities that will have to come into contact with the surface of just operated cornea. The nanostructured surface of the TCL also excludes the growth of fibrous tissue in the underlying space of the TCL. In the cases of the observed eyes, the desired positive postoperative result of healing and restoration of living tissues was achieved in 100% of cases.
One of the most positive aspects of surface nanomodification technology is the possibility of simultaneous surface modification and its sterilization. The characteristic properties of the SCL surface provided by the use of surface Nano structurization are also: lack of toxicity, surface biocompatibility, certain adhesive and repulsive properties for certain living cells and their elements, which determines the desired properties of nano coatings. That is, such a polymer surface treatment improves the quality and safety of polymer products widely used in medicine and biology.

Keywords: Therapeutic Contact Lenses; Eyeball; Biology

References

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Citation

Citation: Alvina D Musina. “Therapeutic Contact Lenses with a Nanomodified Surface for Corneal Rehabilitation After Donor Corneal Transplantation or Other Ophthalmosurgical Interventions on the Anterior Segment of the Eyeball".Acta Scientific Ophthalmology 7.1 (2024): 30-35.

Copyright

Copyright: © 2024 Alvina D Musina. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.