Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 6 Issue 12

Artificial Iris Surface Modification by Means of Carbon Film Deposition for Providing the Eye Diaphragm Loss Compensation

Alvina D Musina1* and Eugene E Sidorenko2

1Senior Scientist, PhD, Ophthalmologist, Moscow, Russia
2Professor, PhD, Head of the Department of Scientific-Practical Centre, Moscow, Russia

*Corresponding Author: Alvina D Musina, Senior Scientist, PhD, Ophthalmologist, Moscow, Russia.

Received: October 02, 2023; Published: November 23, 2023


New medical products, materials and surgical procedures keep improving current health-care practices. Many of these innovations involve polymeric devices that must meet certain clinical and costs requirements. Chief among these pressures is the need for biocompatibility between the physiological environment and synthetic biomaterial surface. Carbon Film (CF) such as diamond-like, carbyne, carbyne-containing, carbon nanotubes; deposition for obtaining the materials with nanostructured surface (NSS) can improve synthetic material biocompatibility and biofunctionality.

The aim of our work was artificial iris creation and subsequent sufficient prosthetic replacement of a partial or complete loss of the natural iris diaphragm in eyes. For implantation artificial irises manufactured from polyethyleneterephtalate (PET), polytetrafluorethylene (PTFE) and polyvinilidenefluoride (PVDF) were used with their surface modification by CF deposition. Modification was carried out using CF deposition from directed ion-plasma flows of hydrocarbon vapors or by magnetron deposition.

Implanted iris prosthesis showed in all cases a stabile position. Iris prostheses which surface was modified by means of CF deposition after their implantations permitted the compensation of the native iris absence. NSS of artificial iris excluded fibrous tissue proliferation. Experimental eyes achieved the desired anatomic result.

Implantations of prosthetic iris devices manufactured from PET, PTFE, PVDF and covered by CF deposition showed the required results for eye diaphragm loss compensation. One of most convenient aspect of CF deposition technology is the potential for simultaneous surface modification and sterilization. Obligatory properties of artificial iris surface provided with CF deposition: the absence of toxicity, biocompatibility, and dispersed surface, certain adhesive and repelling for cells and the properties of chemical compounds can give a possibility of a successful application for this artificial substitute.

Keywords: Carbon Film (CF); Nanostructured Surface (NSS); Polytetrafluorethylene (PTFE)


  1. Langer R and Vacanti JP. “Tissue engineering”. Journal of Science 260 (1933): 920-925.
  2. Mohammad A Heidaran. “Tissue Engineering; Review article”. Iranian Biomed Journal 4 (2000): 1-5.
  3. Sundmacher R., et al. “Black-diaphragm intraocular lens for correction of aniridia”. Journal of Ophthalmic Surgery 25 (1994): 180-185.
  4. Reinhard T., et al. “Irisblenden-IOL bei traumtischer aniridie”. Klin Monatsbl Augenheilkd 205 (1994): 196-200.
  5. Sundmacher R., et al. “Black diaphragm intraocular lens in congenital aniridia”. German Journal of Ophthalmology 3 (1994): 197-201.
  6. Thompson CG., et al. “Implantation of a black diaphragm intraocular lens for traumatic aniridia”. Journal of Cataract and Refractive Surgery 25 (1999): 808-813.
  7. Tanzer DJ and Smith RE. “Black iris-diaphragm intraocular lens for aniridia and aphakia”. Journal of Cataract and Refractive Surgery 25 (1999): 1548-1551.
  8. Osher RH and Burk SE. “Cataract surgery combined with implantation of an artificial iris”. Journal of Cataract and Refractive Surgery 25 (1999): 1540-1547.
  9. Reinhard T., et al. “Black diaphragm aniridia intraocular lens for congenital aniridia: long-term follow-up”. Journal of Cataract and Refractive Surgery 26 (2000): 375-381.
  10. Burk SE., et al. “Prosthetic iris implantation for congenital, traumatic, or functional iris deficiencies”. Journal of Cataract and Refractive Surgery 27 (2001): 1732-1740.
  11. Mavrikakis I and Hickman Casey JM. “Phacoemulsification and endocapsular implantation of an artificial iris intraocular lens in traumatic cataract and aniridia”. Journal of Cataract and Refractive Surgery 28 (2002): 1088-1091.
  12. IH Loh and DM Hudson. “Polymerization Process”, U.S. Patent, no. 5 (1995): 447,799.
  13. MS Sheu., et al. “Biomaterials Surface Modification Using Plasma Gas Discharge Processes”, in Encyclopedic Handbook of Biomaterials and Bioengineering, Part A. Materials, edited by DL Wise, D.J.Trantolo, D.E. Altobelli, M.J. Yaszemski, J.D.Gresser and E.R. Schwartz, Marcer Dekker, New York 1 (1995): 865-894.
  14. BD Ratner., et al. “Plasma Deposition and Treatment for Biomedical Applications,” in Plasma Deposition, Treatment and Etching of Polymers, edited by R. d'Agostino, Academic Press, San Diego, CA, 463-516; (1990).
  15. VM Elinson., et al. “Barrier properties of carbon films deposited on polymer-based devices in aggressive environments". Diamond and Related Materials 8 (1999): 2103-2109.
  16. PT Jacobs and SM Lin. “Hydrogen Peroxide Plasma Sterilization System”. U.S. Patent, 4,643,876 and 4,756,882 (1987).


Citation: Alvina D Musina and Eugene E Sidorenko. “Artificial Iris Surface Modification by Means of Carbon Film Deposition for Providing the Eye Diaphragm Loss Compensation".Acta Scientific Ophthalmology 6.12 (2023): 45-49.


Copyright: © 2023 Alvina D Musina and Eugene E Sidorenko. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In

News and Events

Contact US