Asaad Ahmed Ghanem*

Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Egypt

*Corresponding Author: Asaad Ahmed Ghanem, Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Egypt.

Received: August 27, 2023; Published: October 16, 2023

Abstract

The main routes of drug administration and elimination from the eye. Through the following processes: 1) transcorneal permeation from the lacrimal fluid into the anterior chamber, 2) non-corneal drug permeation across the conjunctiva and sclera into the anterior uvea, 3) drug distribution from the blood stream via blood-aqueous barrier into the anterior chamber, 4) elimination of drug from the anterior chamber by the aqueous humor turnover to the trabecular meshwork and Sclemm's canal, 5) drug elimination from the aqueous humor into the systemic circulation across the blood-aqueous barrier, 6) drug distribution from the blood into the posterior eye across the blood-retina barrier, 7) intravitreal drug administration, drug elimination from the vitreous via posterior route across the blood-retina barrier, and 9) drug elimination from the vitreous via anterior route to the posterior chamber.

References

Citation

Citation: Asaad Ahmed Ghanem. “New Concepts of Ocular Pharmacokinetics". Acta Scientific Ophthalmology 6.11 (2023): 04-05.

Copyright

Copyright: © 2023 Asaad Ahmed Ghanem. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.