Demodex the Enemy Behind Our Lines
Ghaleb F Seif*
MRCSed, FICO Head of Ophthalmology Department, NMC Royal Hospital, Khalifa City, Abu Dhabi, United Arab Emirates
*Corresponding Author: Ghaleb F Seif, MRCSed, FICO Head of Ophthalmology Department, NMC Royal Hospital, Khalifa City, Abu Dhabi, United Arab Emirates.
Received:
February 15, 2023; Published: April 12, 2023
Abstract
Demodex blepharitis is a common ocular condition caused by an infestation of Demodex mites on the eyelids and eyelashes. This brief review provides an overview of the epidemiology, clinical presentation, diagnosis, and management of Demodex blepharitis. The article discusses risk factors associated with the condition, such as age and poor hygiene, and highlights various diagnostic tests that are available. Management strategies, including lid hygiene and medications, are also presented. The review emphasizes the importance of early diagnosis and effective management to improve visual function and minimize ocular discomfort.
Keywords: Demodex; Demodex folliculorum; Demodex Blepharitis
References
- Elston CA and Elston DM. “Demodex mites”. Clinics in Dermatology 32 (2014): 739-743.
- Schear MJ., et al. “The Association of Demodex with Chalazia: A Histopathologic Study of the Eyelid”. Ophthalmic Plastic and Reconstructive Surgery 4 (2016): 275-278.
- Holmes AD. “Potential role of microorganisms in the pathogenesis of rosacea”. Journal of the American Academy of Dermatology6 (2013): 1025-1032.
- Zhao YE., et al. “Association of blepharitis with Demodex: a meta-analysis”. Ophthalmic Epidemiology2 (2012): 95-102.
- Chen W and Plewig G. “Are Demodex Mites Principal, Consipiratory, Accomplice, Witness or Bystander in the Cause of Rosacea?”. American Journal of Clinical Dermatology 16 (2015): 67-72.
- Cheng A., et al. “Recent advances on ocular Demodex infestation”. Current Opinion in Ophthalmology 26 (2015): 295-300.
- Liu J., et al. “Pathogenic role of Demodex mites in blepharitis”. Current Opinion in Allergy and Clinical Immunology 5 (2010): 505-510.
- Nicholls S., et al. “Demodex species in human ocular disease: new clinicopathological aspects”. International Ophthalmology (2016).
- Gao Y., et al. “High prevalence of Demodex in eyelashes with cylindrical dandruff”. Investigative Ophthalmology and Visual Science 9 (2005): 3089-3094.
- Liang L., et al. “High prevalence of Demodex brevis infestation in chalazia”. American Journal of Ophthalmology 2 (2014): 342-348.
- Yamaoka T., et al. “Severe rosacea with prominent Demodex folliculorum in a patient with HIV”. Journal of Dermatology2 (2014): 195-196.
- Kheirkhah A., et al. “Fluorescein dye improves microscopic evaluation and counting of Demodex in blepharitis with cylindrical dandruff”. Cornea6 (2007): 697-700.
- Turqut B., et al. “Phthriasis palpebrarum mimicking lid eczema and blepharitis”. Journal of Ophthalmology 2009 (2009): 803951.
- Gao Y., et al. “Clinical treatment of ocular demodecosis by lid scrub with tea tree oil”. Cornea 26 (2007): 136-143.
- Tighe S., et al. “Terpinen-4-ol is the Most Active Ingredient of Tea Tree Oil to Kill Demodex Mites”. Translational Vision Science and Technology 7 (2013): 2.
- Parvaiz Anwar Rather IH. “Human Demodex Mite: The Versatile Mite of Dermatological Importance”. Indian Journal of Dermatology1 (2014): 60-66.
- Jingbo Liu., et al. “Pathogenic role of Demodex mites in blepharitis”. Current Opinion in Allergy and Clinical Immunology 5 (2010): 505-510.
- Cat Nguyen Burkat., et al. “Demodex Infestation”. From EyeWiki (2022).
- N O'Reilly DB. “Demodex-associated bacterial proteins induce neutrophil activation”. British Journal of Dermatology4 (2012): 753-760.
- Jingbo Liu HS. “Pathogenic role of Demodex mites in blepharitis”. Current Opinion in Allergy and Clinical Immunology (2010).
- Yukan Huang HH. “Ocular demodicosis as a risk factor of pterygium recurrence”. Ophthalmology 7 (2013): 1341-1347.
- Tseng SC., et al. “The treatment of Demodex blepharitis with intense pulsed light”. American Journal of Ophthalmology 5 (2011): 832-838.
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