Postoperative Pain Control in Femto-Lasik with the Use of Therapeutic Contact Lenses Soaked in Ketorolac Trometamol 0.45% TCL Soaked in Ketorolac for Pain After Femto-Lasik

Lorena Figueiredo Patricio¹*, Renata Leite de Pinho Tavares², Ramon Coral Ghanem² and Vinícius Coral Ghanem³

¹Fellow in Refractive Surgery at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil
²Ophthalmologist at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil
³Ophthalmologist and Medical Director at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil

*Corresponding Author: Lorena Figueiredo Patricio, Fellow in Refractive Surgery at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil.

Received: February 27, 2023; Published: March 17, 2023

Abstract

Objective: To compare the postoperative pain between patient eyes submitted to femtosecond laser-assisted LASIK after placement of contact lens (TCL) soaked in 0.45% ketorolac trometamol in one eye and placement of a TCL not soaked in the drug solution in the contralateral eye.

Setting: Sadalla Amin Ghanem Eye Hospital in Joinville, SC, Brazil.

Design: A double-blind, randomized, contralateral, prospective clinical study.

Methods: Patients submitted to LASIK with femtosecond laser received the TCL soaked in ketorolac trometamol 0.45% (Acular^® CMC, Allergan, Inc., Irvine, CA) in one eye and a TCL without any medication in the other eye. The laterality selection was done randomly through a drawing. Patients with ocular surface diseases or those on chronic pain medication were excluded. The pain sensation was registered by the patients during 3 postoperative periods. The Wong-Baker Faces pain rating scale (from 0 to 10) was used.

Results: The study involved 64 eyes from 32 patients. The average postoperative pain score 3 hours after surgery in the eyes with TCL + ketorolac was 1.47 ± 2.12, significantly lower than the score among the eyes that received just the TCL, which was 3.31 ± 2.73 (P = 0.004). No statistically significant difference for pain level was observed 6 hours after surgery (P =0.053) and upon awakening the next day (P = 0.081).

Conclusion: The use of TCL soaked in ketorolac trometamol 0.45% safely provides significant pain reduction three hours after femto-LASIK when the pain is most intense.

 Keywords: Pain; LASIK; Femtosecond Laser; Ketorolac; Contact Lenses

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Citation

Citation: Lorena Figueiredo Patricio., et al. “Postoperative Pain Control in Femto-Lasik with the Use of Therapeutic Contact Lenses Soaked in Ketorolac Trometamol 0.45% TCL Soaked in Ketorolac for Pain After Femto-Lasik".Acta Scientific Ophthalmology 6.4 (2023): 18-23.

Copyright

Copyright: © 2022 Lorena Figueiredo Patricio., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.