Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 6 Issue 4

Postoperative Pain Control in Femto-Lasik with the Use of Therapeutic Contact Lenses Soaked in Ketorolac Trometamol 0.45% TCL Soaked in Ketorolac for Pain After Femto-Lasik

Lorena Figueiredo Patricio1*, Renata Leite de Pinho Tavares2, Ramon Coral Ghanem2 and Vinícius Coral Ghanem3

1Fellow in Refractive Surgery at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil
2Ophthalmologist at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil
3Ophthalmologist and Medical Director at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil

*Corresponding Author: Lorena Figueiredo Patricio, Fellow in Refractive Surgery at Sadalla Amin Ghanem Eye Hospital - Joinville/SC, Brazil.

Received: February 27, 2023; Published: March 17, 2023


Objective: To compare the postoperative pain between patient eyes submitted to femtosecond laser-assisted LASIK after placement of contact lens (TCL) soaked in 0.45% ketorolac trometamol in one eye and placement of a TCL not soaked in the drug solution in the contralateral eye.

Setting: Sadalla Amin Ghanem Eye Hospital in Joinville, SC, Brazil.

Design: A double-blind, randomized, contralateral, prospective clinical study.

Methods: Patients submitted to LASIK with femtosecond laser received the TCL soaked in ketorolac trometamol 0.45% (Acular® CMC, Allergan, Inc., Irvine, CA) in one eye and a TCL without any medication in the other eye. The laterality selection was done randomly through a drawing. Patients with ocular surface diseases or those on chronic pain medication were excluded. The pain sensation was registered by the patients during 3 postoperative periods. The Wong-Baker Faces pain rating scale (from 0 to 10) was used.

Results: The study involved 64 eyes from 32 patients. The average postoperative pain score 3 hours after surgery in the eyes with TCL + ketorolac was 1.47 ± 2.12, significantly lower than the score among the eyes that received just the TCL, which was 3.31 ± 2.73 (P = 0.004). No statistically significant difference for pain level was observed 6 hours after surgery (P =0.053) and upon awakening the next day (P = 0.081).

Conclusion: The use of TCL soaked in ketorolac trometamol 0.45% safely provides significant pain reduction three hours after femto-LASIK when the pain is most intense.

 Keywords: Pain; LASIK; Femtosecond Laser; Ketorolac; Contact Lenses


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Citation: Lorena Figueiredo Patricio., et al. “Postoperative Pain Control in Femto-Lasik with the Use of Therapeutic Contact Lenses Soaked in Ketorolac Trometamol 0.45% TCL Soaked in Ketorolac for Pain After Femto-Lasik".Acta Scientific Ophthalmology 6.4 (2023): 18-23.


Copyright: © 2022 Lorena Figueiredo Patricio., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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