Acta Scientific Ophthalmology (ISSN: 2582-3191)

Case Report Volume 6 Issue 4

Multidisciplinary Approach in Management of Behcet’s Disease

Gulzar Mashani1*, Jaya Kaushik2, Dhaivat Shah3 and Ananta Barvey4

1Department of Ophthalmology, Military Hospital Mhow, India
2Department of Ophthalmology, Command Hospital Lucknow, India
3Department of Ophthalmology, Choithram Netralaya, Indore, India
4Bogomolets National Medical University, Kyiv, Ukraine

*Corresponding Author: Gulzar Mashani, Department of Ophthalmology, Military Hospital Mhow, India.

Received: February 13, 2023; Published: March 14, 2023

Abstract

Behcet’s disease (BD), also known as Silk Route disease, is a recurrent systemic inflammatory disorder characterized by oral aphthous ulcers, skin lesions, ocular lesions, and genital ulcerations. Despite multiple studies on the etiopathogenesis of the disease, its exact mechanisms remain undefined. Behçet's disease is most common in Turkey, the Mediterranean basin and Middle and Far East. Though symptoms usually begin to appear between the ages of 20 and 30, anyone can develop this disease at any age. It affects both men and women equally. Out of the 17 criteria proposed for the diagnosis of BD, the most commonly used criteria are the International Study Group (ISG) on BD criteria and the “International Criteria of BD” (ICBD) criteria. We will discuss a case of a 24-year-old male who presented with Fever, Papulonodular trunk lesions, Mucocutaneous lesion – aphthous ulcer, Genital ulcer – over glans, Ciliary conjunctival congestion. On evaluation the patient had acute non-granulomatous anterior uveitis, and along with that he fulfilled all the major criteria for Bechet’s disease. HLA-B51 was also found positive. He was managed with a course of oral as well as topical steroid along with immunomodulator and supportive drugs and the patient recovered well.

 Keywords: Behcet’s disease; Human Leucocyte Antigen; Population

References

  1. U Tursen., et al. “Evaluation of clinical findings according to sex in 2313 Turkish patients with Behçet's disease”. International Journal of Dermatology5 (2003): 346-351.
  2. Sakane T., et al. “Behçet’s disease”. The New England Journal of Medicine 341 (1999): 1284-1291.
  3. Jennette JC., et al. “2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides”. Arthritis and Rheumatology 65 (2013): 1-1.
  4. Kaklamani VG., et al. “Behçet’s disease”. Seminar on Arthritis and Rheumatology 27 (1998): 197-217.
  5. Pande I., et al. “Behçet’s disease in India: A clinical, immunological, immunogenetic and outcome study”. British Journal of Rheumatology 34 (1995): 825-830.
  6. Sachdev N., et al. “Spectrum of Behçet’s disease in the Indian population”. International Ophthalmology 29 (2009): 495-501.
  7. Singal A., et al. “Behçet’s disease in India: A dermatological perspective”. Indian Journal of Dermatology, Venereology and Leprology L79 (2013): 199-204.
  8. Tan SY and Poole PS. “Hulusi Behçet (1889-1948): Passion for dermatology”. Singapore Medical Journal 57 (2016): 408-409.
  9. Zouboulis CC and Kaklamanis P. “Early descriptions of Adamantiades Behçet’s disease”. Annals of the Rheumatic Diseases 62 (2003): 691-692.
  10. Davatchi F., et al. “The saga of diagnostic/classification criteria in Behcet’s disease”. International Journal of Rheumatic Diseases 18 (2015): 594-605.
  11. Maldini C., et al. “Relationships of HLA-B51 or B5 genotype with Behcet’s disease clinical characteristics: Systematic review and meta-analyses of observational studies”. Rheumatology (Oxford) 51 (2012): 887-900.
  12. Sequeira FF and Daryani D. “The oral and skin pathergy test”. Indian Journal of Dermatology, Venereology and Leprology 77 (2011): 526-530.
  13. Mir T., et al. “Clinical profile of classical Fever of Unknown Origin (FUO)”. Caspian Journal of Internal Medicine 5 (2014): 35-39.
  14. Samad T., et al. “Behcets disease presenting as fever of unknown origin: A case report”. BIRDEM Medical Journal 3 (2013): 50-53.
  15. Fatima J., et al. “Behçet’s syndrome presenting as FUO”. Journal of the Association of Physicians of India 58 (2010): 331-332.
  16. Tugal-Tutkun I., et al. “Uveitis in Behcet disease: An analysis of 880 patients”. American Journal of Ophthalmology 138 (2004): 373-380.
  17. Evereklioğlu C. “Ocular Behcet disease: Current therapeutic approaches”. Current Opinion in Ophthalmology 22 (2011): 508-516.
  18. Zierhut M., et al. “Behçet’s disease”. In: Pleyer U, Mondino B, editors. Essentials in Ophthalmology: Uveitis and Immunological Disorders. 1st Berlin: Springer-Verlag Berlin Heidelberg (2005): 173-200.
  19. Namba K., et al. “A major review: Current aspects of ocular Behçet’s disease in Japan”. Ocular Immunology and Inflammation 23 (2015): 1-23.

Citation

Citation: Gulzar Mashani., et al. “Multidisciplinary Approach in Management of Behcet’s Disease".Acta Scientific Ophthalmology 6.4 (2023): 14-17.

Copyright

Copyright: © 2022 Gulzar Mashani., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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