Ali Nouraeinejad*

Ph.D. in Clinical Ophthalmology, Department of Clinical Ophthalmology, University College London (UCL), London, United Kingdom

*Corresponding Author: Ali Nouraeinejad, Ph.D. in Clinical Ophthalmology, Department of Clinical Ophthalmology, University College London (UCL), London, United Kingdom.

Received: November 28, 2022; Published: January 01, 2023

Clinical procedures, such as refractive surgeries, depend on the counts of corneal cells and their nerves placed at en face corneal planes and consequently need en face corneal images with a large field-of-view [1]. However, the field-of-view of current high-resolution clinical methods, such as in vivo confocal microscopy (IVCM) and specular microscopy (SM), is optically restricted to about 0.5 mm [1,2]. Emerging in vivo research instruments derived from conventional Fourier-domain optical coherence tomography (OCT), such as ultrahigh-resolution-OCT (UHR-OCT) [3,4], Gabor-domain optical coherence microscopy (GDOCM) [5], and micro-OCT (µOCT) [6] can amplify the field-of-view up to about 1 mm; however, the cellular mosaics at that level are free of motion artifacts only in anaesthetized humans and animals, immobilized throughout the prolonged laser beam scanning in the en face plane [2].

References

1. Nouraeinejad A. “Differential Diagnosis in Optometry and Ophthalmology”. Second Edition. Iran: Noruzi Publication (2017).
2. Mazlin V., et al. “Curved-field optical coherence tomography: large-field imaging of human corneal cells and nerves”. Optica6 (2020): 872-880.
3. Tan B., et al. “250 kHz, 1.5 µm resolution SD-OCT for in-vivo cellular imaging of the human cornea”. Biomedical Optics Express 12 (2018): 6569-6583.
4. Yao X., et al. “In vivo corneal endothelium imaging using ultrahigh resolution OCT”. Biomedical Optics Express 10 (2019): 5675-5686.
5. Canavesi C., et al. “In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy”. Biomedical Optics Express 2 (2020): 711-724.
6. Chen S., et al. “Visualizing Micro-anatomical Structures of the Posterior Cornea with Micro-optical Coherence Tomography”. Scientific Report1 (2017): 10752.

Citation

Citation: Ali Nouraeinejad. “Improvement in Corneal Assessment by Curved-field OCT".Acta Scientific Ophthalmology 6.2 (2023): 01-02.

Copyright

Copyright: © 2022 Ali Nouraeinejad. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.