Nirupam Chowdhury¹*, Md Sharfuddin Ahmed², Md. Showkat Kabir³, Chandan Kumar Roy⁴, Md Moinul Hoque⁵, Subarna Saha⁶, Mohammad Shish Rahman⁷ and Nawreen Binte Anwar⁸

¹Assistant Professor, Department of Community Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
²Vice Chancellor, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
³Professor, Chairman of department of Community Ophthalmology, Bangbandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁴Associate Professor, Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁵Associate Professor, Department of Community Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁶Medical Officer, Department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁷Associate Professor, Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁷Associate Professor, Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
⁸Medical Officer, Department of Community Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

*Corresponding Author:Nirupam Chowdhury, Assistant Professor, Department of Community Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Received: October 07, 2022; Published: October 27, 2022

Abstract

Purpose: The purpose of the study was to assess the bacterial spectrum in patients with chronic dacryocystitis and their antibiotic sensitivity pattern.

Methods: This cross-sectional observational study was carried out in the Department of Ophthalmology, Department of Community Ophthalmology and Department of Microbiology and Immunology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from March 2017 to August 2019. A total of 50 patients of 19 years and above with clinically diagnosed cases of chronic dacryocystitis were enrolled in this study.

Results: Most of the patients belonged to 46-55 years of age and male to female ratio was 1:2.8. All the Gram negative organisms were 100% resistant to Amoxycillin and 100% sensitive to Tobramycin. housewives followed by 8 (16%) service holders and 7 (14%) businessmen. More than one third (34.0%) of the patients were culture positive and 66.0% were culture negative. Four cases had Gram positive bacteria; among them 3 (75%) were Staphylococcus aureus. Thirteen patients had Gram negative bacteria, among which Klebsiella spp was found in 9 (69.2%). The most common isolated bacterial organisms were Klebsiella spp 9(52.9%) followed by Staphylococcus aureus 3(17.6%) and Acinetobacter Spp 2(11.8%). In Gram positives Staphylococcus aureus and Streptococcus pyogenes had maximum sensitivity to Amoxycillin (100.0%), Chloramphenicol (100.0%), Tobramycin (100.0%), Ceftazidime (100.0%) and Gentamycin (100.0%). All the Gram negative organisms were 100% resistant to Amoxycillin and 100% sensitive to Tobramycin. Klebsiella spp was maximum sensitive to Tobramycin (100%) and Ceftazidime (100%).

Conclusion: Bacterial pathogens among Gram positive isolate was Staphylococcus aureus and Streptococcus pyogenes 100% sensitivity to Amoxycillin, Chloramphenicol, Tobramycin, Ceftazidime and Gentamycin whereas Gram negative had shown resistance to Amoxycillin.

Keywords: Dacryocystitis; Nasolacrimal Duct; Bacteria; Culture and Sensitivity; Epiphora

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Citation

Citation: Nirupam Chowdhury., et al. “Bacterial Spectrum and Antibiotic Sensitivity in Patients with Chronic Dacryocystitis Attending at a Tertiary Hospital in Dhaka".Acta Scientific Ophthalmology 5.11 (2022): 13-19.

Copyright

Copyright: © 2022 Nirupam Chowdhury., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.