Madhuvanthi Mohan, Sashwanthi Mohan*, Sujatha Mohan and Mohan Rajan

Rajan Eye Care Hospital, Chennai, Tamilnadu, India

*Corresponding Author: Sashwanthi Mohan, Rajan Eye Care Hospital, Chennai, Tamilnadu, India.

Received: August 08, 2022; Published: September 07, 2022

• Myasthenia gravis is an autoimmune, neuromuscular junction disorder causing fatiguability and weakness of the muscles [1].
• Ocular myasthenia gravis (OMG) is where weakness is isolated to the periocular muscles, namely, extraocular muscles, levator palpebrae superioris and orbicularis oculi [2].
• Extraocular muscles (EOMs) are more commonly affected as they contain twitch fibers.
• These twitch fibres develop tension faster and have a higher frequency of synaptic firing than limb muscles.
• They are more susceptible to fatigue.
• Tonic muscle fibers are needed to maintain the gaze in any direction.
• This type of fiber has fewer acetyl choline receptors, making them prone to receptor loss and damage [3].
• Ptosis and diplopia are usually the presenting signs in these patients [4].
• There is a stronger predilection in males [2,3].

References

1. Nair AG., et al. “Ocular myasthenia gravis: a review”. Indian Journal of Ophthalmology10 (2014): 985-991.
2. Grigg J. “Extraocular muscles: Relationship of structure and function to disease”. Australian and New Zealand Journal of Ophthalmology 27 (1999): 369‐370.
3. Sommer N., et al. “Ocular myasthenia gravis. A critical review of clinical and pathophysiological aspects”. Documenta Ophthalmologica 84 (1993): 309-333.
4. Grob D., et al. “The course of myasthenia gravis and therapies affecting outcome”. Annals of the New York Academy of Sciences 505 (1987): 472-499.
5. Sethi KD., et al. “Ice pack test for myasthenia gravis”. Neurology 37 (1987): 1383-1395.
6. Juel VC and Massey JM. “Myasthenia gravis”. Orphanet Journal of Rare Diseases 2 (2007): 44.
7. Costa J., et al. “Repetitive nerve stimulation in myasthenia gravis - relative sensitivity of different muscles”. Clinical Neurophysiology 115 (2004): 2776-2782.
8. Chen CS., et al. “Double vision in a patient with thyroid disease: What’s the big deal?” Survey on Ophthalmology 52 (2007): 434‐439.
9. Osserman KE., et al. “Myasthenia gravis and thyroid disease: Clinical and immunologic correlation”. J Mount Sinai Hospital N Y 34 (1967): 469‐83.

Citation

Citation: Sashwanthi Mohan., et al. “Tests to Diagnose Ocular Myasthenia Gravis".Acta Scientific Ophthalmology 5.10 (2022): 06-07.

Copyright

Copyright: © 2022 Sashwanthi Mohan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.