Acta Scientific Ophthalmology (ISSN: 2582-3191)

Short Communication Volume 5 Issue 9

The Requirement of Clinically Validated Technologies for Blinking Analysis

Ghasem Yazdanpanah*

Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Illinois, USA

*Corresponding Author: Ghasem Yazdanpanah, Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Illinois, USA.

Received: August 01, 2022; Published: August 19, 2022

The eyelids are not only provide physical protection of the ocular surface, but also have a significant role in homeostasis of the ocular surface by performing blinking [1]. Blinking is a vital function of the eyelids which redistributes the tear film and stabilizes the ocular surface [2]. Mechanism of blinking is precisely regulated [3] which is important in temporarily boosting the visual performance [4]. Ineffective blinking leads to unstable tear film and ultimately to several ocular surface diseases including dry eye disease [2]. Examples of dysfunctional blinking are incomplete blinks, high blink velocity, short blink intervals, forceful blinking, and low (<10/min) or high (>25/min) blink rates. The changes in blinking quality and rate could be (1) a response to ocular surface diseases, e.g. dry eye disease, or (2) primarily originated from neurologic or systemic diseases, e.g. benign essential blepharospasm or Parkinson’s disease which leads to ocular surface and tear film destabilization [5,6].


  1. X Zhang., et al. “Dry Eye Management: Targeting the Ocular Surface Microenvironment”. International Journal of Molecular Sciences 7 (2017).
  2. MTM Wang., et al. “Impact of blinking on ocular surface and tear film parameters”. Ocular Surface4 (2018): 424-429.
  3. LJ Bour., et al. “Neurophysiological Aspects of Eye and Eyelid Movements During Blinking in Humans”. Journal of Neurophysiology1 (2000): 166-176.
  4. JWA Ang and GW Maus. “Boosted visual performance after eye blinks”. Journal of Vision10 (2020): 2-2.
  5. C Evinger., et al. “Dry eye, blinking, and blepharospasm”. Movement Disorders 2 (2002) S75-78.
  6. R Sandyk. “The significance of eye blink rate in parkinsonism: a hypothesis”. Interntaional Journal of Neuroscience1-2 (1990): 99-103.
  7. T Mitchell., et al. “Video Viewing Blink Rate in Normal and Dry Eyes”. Eye Contact Lens8 (2021) 442-444.
  8. A Dementyev., et al. “DualBlink: A Wearable Device to Continuously Detect, Track, and Actuate Blinking For Alleviating Dry Eyes and Computer Vision Syndrome”. Interactive, Mobile, Wearable and Ubiquitous Technologies (2017): 19.
  9. J Espinosa., et al. “Comparative analysis of spontaneous blinking and the corneal reflex”. Royal Society Open Science 12 (2020) 201016.
  10. X Jiang., et al. “Capturing and evaluating blinks from video-based eyetrackers”. Behavior Research Methods3 (2013): 656-663.
  11. DH Szczesna., et al. “Predicting dry eye using noninvasive techniques of tear film surface assessment”. Investigative Ophthalmology and Visual Science2 (2011): 751-756.
  12. K Tsubota., et al. “Quantitative videographic analysis of blinking in normal subjects and patients with dry eye”. Archives of Ophthalmology6 (1996): 715-720.
  13. G Yazdanpanah., et al. “Change in Blink Rate Following Botulinum Toxin Injection in Benign Essential Blepharospasm”. Investigative Ophthalmology and Visual Science7 (2022): 607-A0308-607-A0308.
  14. DL Ashwini., et al. “Efficacy of blink software in improving the blink rate and dry eye symptoms in visual display terminal users - A single-blinded randomized control trial”. Indian Journal of Ophthalmology10 (2021): 2643-2648.
  15. DS Nosch., et al. “Blink Animation Software to Improve Blinking and Dry Eye Symptoms”. Optometry and Vision Science 9 (2015): e310-315.
  16. Y Su., et al. “Spontaneous Eye Blink Patterns in Dry Eye: Clinical Correlations”. Investigative Ophthalmology and Visual Science12 (2018): 5149-5156.
  17. FHW Mak., et al. “Videographic Analysis of Blink Dynamics following Upper Eyelid Blepharoplasty and Its Association with Dry Eye”. Plastic and Reconstructive Surgery – Global Open7 (2020): e2991.


Citation: Ghasem Yazdanpanah. “The Requirement of Clinically Validated Technologies for Blinking Analysis".Acta Scientific Ophthalmology 5.9 (2022): 26-27.


Copyright: © 2022 Ghasem Yazdanpanah. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 15, 2022.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US