Acta Scientific Ophthalmology (ISSN: 2582-3191)

Case Report Volume 5 Issue 8

Lower Eyelid Conjunctival Amyloidosis: A Case Report

Anna Gkountelia* and Wessam Mina

Department of Ophthalmology, BHRUT Hospitals, Queen’s Hospital, London, United Kingdom

*Corresponding Author: Anna Gkountelia, Department of Ophthalmology, BHRUT Hospitals, Queen’s Hospital, London, United Kingdom.

Received: May 16, 2022; Published: July 12, 2022

Abstract

Amyloidosis is characterized by extracellular deposition of protein amyloid fibrils in tissues, including conjunctiva, which are insoluble in proteolytic proteins. Conjunctival amyloidosis specifically in the palpebral conjunctiva is a rare finding in clinical practice [1,4,5,7,10]. The authors described the case of a 37-year-old Bangladeshi origin female patient, with lesion located in the lower eyelid conjunctiva, elevated, well-defined, yellowish. Incisional biopsy of the lesion was performed, and the histological examination confirmed conjunctival amyloidosis. Conjunctival amyloidosis is a rare finding in the literature. The management of conjunctival amyloidosis depends on the extent of local involvement and patient’s general health status, varying from symptomatic, with use of ocular lubricants, to surgical, by removing the lesions.

Keywords: Conjunctival Amyloidosis; Eyelid; Amyloid Fibrils

References

  1. E R Mora-Horna., et al. “Ocular adnexal and orbital amyloidosis: a case series and literature review”. International Ophthalmology2 (2016): 281-298.
  2. S Dinakaran., et al. “Orbital amyloidosis presenting as ptosis”. Eye1 (2005): 110-112.
  3. C Tyradellis., et al. “Surgical management of recurrent localized eyelid amyloidosis”. Ophthalmic Plastic and Reconstructive Surgery4 (2006): 308-309.
  4. JD Gillmore and PN Hawkins. “Pathophysiology and treatment of systemic amyloidosis”. Nature Reviews Nephrology10 (2013): 574-586.
  5. D Suesskind., et al. “Conjunctival amyloidosis—clinical and histopathologic features”. Graefe's Archive for Clinical and Experimental Ophthalmology8 (2015): 1377-1383.
  6. Caggiati A., et al. “Primary amyloidosis of the eyelid: a case report”. In Vivo4 (2010): 575-578.
  7. HA Hussain and DP Edward. “Anterior orbit and adnexal amyloidosis”. Middle East African Journal of Ophthalmology3 (2013): 193-197.
  8. RW Pelton., et al. “Nodular cutaneous amyloid tumors of the eyelids in the absence of systemic amyloidosis”. Ophthalmic Surgery and Lasers 5 (2001): 422-424.
  9. L J Correa., et al. “Systemic amyloidosis with bilateral conjunctival involvement: a case report”. BMC Ophthalmology1 (2015).
  10. B O'Donnell., et al. “Amyloidosis of the conjunctiva”. Australian and New Zealand Journal of Ophthalmology3 (1995): 207-212.
  11. R Cheong-Leen. “Primary localised conjunctival amyloidosis presenting as subconjunctival haemorrhage”. Eye5 (2001): 679-680.
  12. G T Higgins., et al. “Recurrent subconjunctival and periorbital haemorrhage as the first presentation of systemic AL amyloidosis secondary to myeloma”. Eye4 (2006): 512-515.
  13. H L Nienhuis., et al. “The prevalence and management of systemic amyloidosis in Western Countries”. Kidney Diseases1 (2016): 10-19.

Citation

Citation: Anna Gkountelia and Wessam Mina. “Lower Eyelid Conjunctival Amyloidosis: A Case Report".Acta Scientific Ophthalmology 5.8 (2022): 09-11.

Copyright

Copyright: © 2022 Anna Gkountelia and Wessam Mina. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is September 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US