Visual Evoked Potential in Myopia
Mona Abdelkader* and Ayman Fawzy
Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Egypt
*Corresponding Author: Mona Abdelkader, Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Egypt.
April 04, 2022; Published: April 18, 2022
Purpose: To determine how the magnitude of myopia influences the parameters of pattern visual evoked potential (VEP) and multifocal visual evoked potential (MVEP).
Subjects and Methods: One hundred and eighty eyes of 180 normal volunteers with good visual acuity and without glaucoma were included in the study. The subjects were divided into four groups.
The groups were emmetropia with refractive error (±0.25D), low myopia (-0.25D to -4.00D), Moderate myopia (-4.2SD to -8.00D) and high myopia (>-8.00D). All subjects were tested on flash VEP, pattern VEP, multifocal visual evoked potential (M-VEP) and static automated perimetry (SAP).
M-VEP positive peak wave (p) amplitude and latency were measured for all groups. Also,P100 amplitude and latency of PVEP were detected. Mean deviations (MD) and Corrected pattern standard deviation (CPSD) of SAP were determined. The relationship between refractive error, PVEP, M-VEP parameters and SAP values were assessed.
Results: For low myopia, there were no significant correlation between SAP values and spherical equivalent. For moderate and high myopia, there were decrease in mean sensitivity and mean deviation as degree of myopia increase. While both PVEP and M-VEP amplitudes and latencies in mild and moderate myopia were similar to emmetropia, in high myopia, P wave amplitude decreased and P wave latency increased slightly.
Conclusion: Low and moderate myopia does not alter the visual field obtained by M-VEP or parameters of PVEP with slight affection of VEP parameters in high myopia.
Keyword: Myopia; Multifocal Visual Evoked Potential; PVEP; SAP
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