Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 5 Issue 3

Comparing the Effect of Penetrating Canaloplasty and Trabeculectomy in Pseudophakic Chronic Primary Angle Closure Glaucoma Patients

Xiaoyuan Yang, Conghui Ma, Haijun Li, Xin Jin, Jing Ren, Liang Dong, Yangzeng Dong and Zongming Song

Henan Eye Hospital, Henan Eye Institute of Henan Provincial People’s Hospital, China

*Corresponding Author: Zongming Song, Professor, Henan Eye Hospital, Henan Eye Institute of Henan Provincial People’s Hospital, China.

Received: January 25, 2022; Published: February 28, 2022

Abstract

Background: To compare the efficacy and safety of penetrating canaloplasty with partial Schlemm’s canal excision and retention suture to traditional trabeculectomy in the treatment of chronic primary angle closure glaucoma (PACG) in patients who are pseudophakic.

Methods: A Cross Sectional Descriptive study was carried out in Al-Ibrahim eye hospitaThis is a single center prospective comparative cohort study. Eleven consecutive pseudophakic patients (14 eyes) with the diagnosis of chronic primary angle closure glaucoma who were examined at the Henan Eye Institute at Henan Provincial People’s Hospital, between March 2018 and June 2019, were enrolled in the penetrating canaloplasty group. We also retrospectively reviewed the charts of 11 age and gender matched pseudophakic chronic PACG patients (14 eyes) who underwent traditional trabeculectomy the year prior at the same institution. We compared the efficacy and safety between the two surgical intervention groups.
The main outcome measure is surgical success defined as IOP ≤21mmHg without topical IOP lowering medications at 6 months post-operatively. Conditional success defined as IOP ≤21mmHg with topical IOP lowering medications at 6 moths post-operatively.

Results: Six months after the respective surgeries, patients who underwent PC achieved a complete success rate of 85.7%, versus 42.9% in the trabeculectomy group, which is significantly higher (p=0.018).

Conclusion: Compared to traditional trabeculectomy, penetrating canaloplasty with partial SC resection and retention suture might be able to achieve comparable IOP reduction in pseudophakic chronic PACG patients.

Keywords: Canaloplasty; Chronic Primary Angle Closure Glaucoma; Schlemm’s Canal Glaucoma Procedures; Pseudophakic

References

  1. Congdon NG and Friedman DS. “Angle-closure glaucoma: Impact, etiology, diagnosis, and treatment”. Current Opinion in Ophthalmology (2003).
  2. Traverso CE and Cutolo CA. “The effects of phacoemulsification and intraocular lens implantation on anatomical and functional parameters in patients with primary angle closure: A prospective study. (An american ophthalmological society thesis)”. Transactions of the American Ophthalmological Society (2017).
  3. McMillan BD and Gross RL. “Trabeculectomy first in pseudophakic eyes requiring surgery for medically-uncontrolled glaucoma”. Survey of Ophthalmology (2017).
  4. Deng BL., et al. “Surgical treatment for primary angle closure-glaucoma: A meta analysis”. International Journal of Ophthalmology-IJO (2011).
  5. Liang YB and Cheng HH. “Can trabeculectomy go back to “internal drainage?” Ophthalmology China (2018).
  6. Cheng HH., et al. “Preliminary efficacy of penetrating canaloplasty in primary angle-closure glaucoma”. Zhonghua Yan Ke Za Zhi (2019).
  7. Theventhiran A., et al. “A Comparison of Retrobulbar Versus Topical Anesthesia in Trabeculectomy and Aqueous Shunt Surgery”. Journal of Glaucoma (2018).
  8. Song BJ., et al. “Trabeculectomy and combined phacoemulsification-trabeculectomy: Outcomes and risk factors for failure in primary angle closure glaucoma”. Journal of Glaucoma (2016).
  9. Tham CCY., et al. “Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract”. Ophthalmology (2013).
  10. Javanbakht M., et al. “Early lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: An economic evaluation based on data from the EAGLE trial”. BMJ Open (2017).
  11. Muñoz-Negrete FJ., et al. “Guía terapéutica del glaucoma crónico por cierre angular primario”. Archivos de la Sociedad Española de Oftalmología (2015).
  12. Rosin LM and Bell NP. “Preservative toxicity in glaucoma medication: Clinical evaluation of benzalkonium chloride-free 0.5% timolol eye drops”. Clinical Ophthalmology (2013).
  13. How ACS., et al. “A randomised crossover study comparing bimatoprost and latanoprost in subjects with primary angle closure glaucoma”. British Journal of Ophthalmology (2009).
  14. Raina UK and Tuli D. “Trabeculectomy with releasable sutures: A prospective, randomized pilot study”. Archives of Ophthalmology (1998).
  15. Takihara Y., et al. “Trabeculectomy for open-angle glaucoma in phakic eyes vs in pseudophakic eyes after phacoemulsification: A prospective clinical cohort study”. JAMA Ophthalmology (2014).
  16. Emanuel ME., et al. “Evidence-based management of primary angle closure glaucoma”. Current Opinion in Ophthalmology (2014).
  17. Chen J and Sun X. “How to make an appropriate choice of glaucoma surgery”. Zhonghua Shiyan Yanke Zazhi/Chinese Journal of Clinical and Experimental Ophthalmology (2018).
  18. Wang N., et al. “The comparison of short-term outcome between aqueous drainage pathway reconstruction surgery versus canaloplasty for open angle glaucoma”. Chinese Journal of Ophthalmology (2014).
  19. Baig N., et al. “Managing Primary Angle Closure Glaucoma – The Role of Lens Extraction in this Era”. The Open Ophthalmology Journal (2016).
  20. Budenz DL., et al. “Postoperative Complications in the Ahmed Baerveldt Comparison Study during Five Years of Follow-up”. American Journal of Ophthalmology (2016).
  21. Lindemann F., et al. “Three-Year Follow-Up of Trabeculectomy with 5-Fluorouracil”. Ophthalmic Research (2017).
  22. Panarelli JF., et al. “A retrospective comparison of primary baerveldt implantation versus trabeculectomy with mitomycin C”. Ophthalmology (2016).
  23. Bull H., et al. “Three-year canaloplasty outcomes for the treatment of open-angle glaucoma: European study results”. Graefe's Archive for Clinical and Experimental Ophthalmology (2011).
  24. Zhou M., et al. “Trabeculectomy with versus without releasable sutures for glaucoma: A meta-analysis of randomized controlled trials”. BMC Ophthalmology (2014).
  25. Lewis RA., et al. “Canaloplasty: Circumferential viscodilation and tensioning of Schlemm canal using a flexible microcatheter for the treatment of open-angle glaucoma in adults. Two-year interim clinical study results”. Journal of Cataract and Refractive Surgery (2009).

Citation

Citation: Zongming Song., et al. Comparing the Effect of Penetrating Canaloplasty and Trabeculectomy in Pseudophakic Chronic Primary Angle Closure Glaucoma Patients".Acta Scientific Ophthalmology 5.3 (2022): 65-73.

Copyright

Copyright: © 2022 Zongming Song., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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