Comparing the Effect of Penetrating Canaloplasty and Trabeculectomy in
Pseudophakic Chronic Primary Angle Closure Glaucoma Patients
Xiaoyuan Yang, Conghui Ma, Haijun Li, Xin Jin, Jing Ren, Liang Dong, Yangzeng Dong and Zongming Song
Henan Eye Hospital, Henan Eye Institute of Henan Provincial People’s Hospital, China
*Corresponding Author: Zongming Song, Professor, Henan Eye Hospital, Henan
Eye Institute of Henan Provincial People’s Hospital, China.
January 25, 2022; Published: February 28, 2022
Background: To compare the efficacy and safety of penetrating canaloplasty with partial Schlemm’s canal excision and retention suture to traditional trabeculectomy in the treatment of chronic primary angle closure glaucoma (PACG) in patients who are pseudophakic.
Methods: A Cross Sectional Descriptive study was carried out in Al-Ibrahim eye hospitaThis is a single center prospective comparative cohort study. Eleven consecutive pseudophakic patients (14 eyes) with the diagnosis of chronic primary angle closure glaucoma who were examined at the Henan Eye Institute at Henan Provincial People’s Hospital, between March 2018 and June 2019, were enrolled in the penetrating canaloplasty group. We also retrospectively reviewed the charts of 11 age and gender matched pseudophakic chronic PACG patients (14 eyes) who underwent traditional trabeculectomy the year prior at the same institution. We compared the efficacy and safety between the two surgical intervention groups.
The main outcome measure is surgical success defined as IOP ≤21mmHg without topical IOP lowering medications at 6 months post-operatively. Conditional success defined as IOP ≤21mmHg with topical IOP lowering medications at 6 moths post-operatively.
Results: Six months after the respective surgeries, patients who underwent PC achieved a complete success rate of 85.7%, versus 42.9% in the trabeculectomy group, which is significantly higher (p=0.018).
Conclusion: Compared to traditional trabeculectomy, penetrating canaloplasty with partial SC resection and retention suture might be able to achieve comparable IOP reduction in pseudophakic chronic PACG patients.
Keywords: Canaloplasty; Chronic Primary Angle Closure Glaucoma; Schlemm’s Canal Glaucoma Procedures; Pseudophakic
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